Evidence map›Paper›PMID 36238310›Full record

ArticleFrontiers in immunology2022

Hemp seed significantly modulates the endocannabinoidome and produces beneficial metabolic effects with improved intestinal barrier function and decreased inflammation in mice under a high-fat, high-sucrose diet as compared with linseed.

Rim Ben Necib, Claudia Manca, Sébastien Lacroix, Cyril Martin, Nicolas Flamand, Vincenzo Di Marzo, Cristoforo Silvestri

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Frontiers in chemistry · 2024
    Article
  7. Recent Research onMolecules (Basel, Switzerland) · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rim Ben NecibCentre De Recherche De l'Institut Universitaire De Cardiologie Et De Pneumologie De Québec (IUCPQ), Quebec, QC, Canada.
Claudia MancaCentre De Recherche De l'Institut Universitaire De Cardiologie Et De Pneumologie De Québec (IUCPQ), Quebec, QC, Canada.
Sébastien LacroixInstitut Sur La Nutrition Et Les Aliments Fonctionnels (INAF), Quebec, QC, Canada.
Cyril MartinCentre De Recherche De l'Institut Universitaire De Cardiologie Et De Pneumologie De Québec (IUCPQ), Quebec, QC, Canada.
Nicolas FlamandCentre De Recherche De l'Institut Universitaire De Cardiologie Et De Pneumologie De Québec (IUCPQ), Quebec, QC, Canada.
Vincenzo Di MarzoCentre De Recherche De l'Institut Universitaire De Cardiologie Et De Pneumologie De Québec (IUCPQ), Quebec, QC, Canada.
Cristoforo SilvestriCentre De Recherche De l'Institut Universitaire De Cardiologie Et De Pneumologie De Québec (IUCPQ), Quebec, QC, Canada.
Institut Universitaire de Cardiologie et de Pneumologie de Québec · CAUniversité Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omega-3 fatty acids support cardiometabolic health and reduce chronic low-grade inflammation. These fatty acids may impart their health benefits partly by modulating the endocannabinoidome and the gut microbiome, both of which are key regulators of metabolism and the inflammatory response. Whole hemp seeds (

Indexed as

CannabisFatty Acids, Omega-3FlaxInsulinsAnimalsDiet, High-FatFatty AcidsGlucoseHumansInflammationMiceObesityPlasminogen Activator Inhibitor 1SeedsSucroseTriglyceridesFatty AcidsFatty Acids, Omega-3GlucoseInsulinsPlasminogen Activator Inhibitor 1SucroseTriglyceridesendocannabinoidomegut microbiomehemp seedslinseedsnutritionobesityomega-3

Identifiers

PMID36238310
PMCPMC9552265
OpenAlexW4297312471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.