Evidence map›Paper›PMID 36238303›Full record

ArticleFrontiers in immunology2022

Prophylactic treatment of

Zaigham Abbas Rizvi, Prabhakar Babele, Srikanth Sadhu, Upasna Madan, Manas Ranjan Tripathy, Sandeep Goswami, Shailendra Mani, Sachin Kumar, Amit Awasthi, Madhu Dikshit

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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  10. Pharmacological potential ofFrontiers in immunology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zaigham Abbas RizviImmuno-Biology Lab, Infection and Immunology Centre, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Prabhakar BabeleNoncommunicable Disease Centre, Translational Health Science and Technology Institute (THSTI), Faridabad, Haryana, India.
Srikanth SadhuImmuno-Biology Lab, Infection and Immunology Centre, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Upasna MadanImmuno-Biology Lab, Infection and Immunology Centre, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Manas Ranjan TripathyImmuno-Biology Lab, Infection and Immunology Centre, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Sandeep GoswamiImmuno-Biology Lab, Infection and Immunology Centre, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Shailendra ManiNoncommunicable Disease Centre, Translational Health Science and Technology Institute (THSTI), Faridabad, Haryana, India.
Sachin KumarPharmacology Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Amit AwasthiImmuno-Biology Lab, Infection and Immunology Centre, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Madhu DikshitNoncommunicable Disease Centre, Translational Health Science and Technology Institute (THSTI), Faridabad, Haryana, India.
Translational Health Science and Technology Institute · INCentral Drug Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe coronavirus disease (COVID-19) is accompanied by acute respiratory distress syndrome and pulmonary pathology, and is presented mostly with an inflammatory cytokine release, a dysregulated immune response, a skewed neutrophil/lymphocyte ratio, and a hypercoagulable state. Though vaccinations have proved effective in reducing the COVID-19-related mortality, the limitation of the use of vaccine against immunocompromised individuals, those with comorbidity, and emerging variants remains a concern. In the current study, we investigate for the first time the efficacy of the

Indexed as

COVID-19GlycyrrhizaAnimalsCricetinaeCytokinesHumansInterleukin-17Interleukin-4MicePlasminogen Activator Inhibitor 1Reactive Oxygen SpeciesRNA, MessengerSARS-CoV-2CytokinesInterleukin-17Interleukin-4Plasminogen Activator Inhibitor 1Reactive Oxygen SpeciesRNA, MessengerGlycyrrhiza glabrahamster modelmice and human neutrophil functionsNETosisSARS-CoV-2Th2/Th17 differentiation

Identifiers

PMID36238303
PMCPMC9550929
OpenAlexW4297369590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.