Role of Single-Photon Emission Computerised Tomography Versus Ultrasonography or 4D-Computed Tomography in the Management of Primary Hyperparathyroidism.

Chirag Pereira

Abstract read

In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Preoperative localization of single gland disease in primary hyperparathyroidism: a comparative study for preoperative localization with four-dimensional computed tomography, ultrasonography, and technetium-99m-sestamibi single-photon emission computed tomography.Gland surgery · 2025
Article

4 · The record

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5 · Who and what money

Authors and funding

1 author.

Chirag PereiraGeneral Surgery, Royal Lancaster Infirmary, Lancaster, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The aim of the current study was to determine the diagnostic accuracy of three commonly used localization modalities for parathyroid adenomas, i.e., single-photon emission computerised tomography/computed tomography (SPECT/CT), ultrasound (USG) and 4D-computed tomography (4D-CT), especially when used in combination. Methods Medical records of patients diagnosed with primary hyperparathyroidism were reviewed from January 2015 to December 2020. Intra-operative findings were compared with preoperative localization studies (USG, SPECT/CT and 4D-CT) in order to determine sensitivity, specificity and accuracy of these studies. Results One hundred eighty-nine medical records were reviewed. SPECT/CT has a sensitivity of 60.51% and a diagnostic accuracy of 60.21%. USG had the lowest sensitivity of 49.36% with a diagnostic accuracy of 51.6%. 4D-CT had the highest sensitivity of 82.72%, a specificity of 56% and a diagnostic accuracy of 76.42%. When SPECT/CT was used in combination with USG the sensitivity was significantly higher (p=0.0001) at 69.54% and when SPECT/CT was used in combination with 4D-CT the sensitivity was significantly higher at 91.4% (p=0.0001). Conclusions SPECT/CT was more sensitive and accurate as compared to USG but when they were used together the sensitivity was significantly higher. Superior preoperative localization was provided by 4D-CT as compared to SPECT/CT.

Indexed as

4d-ctparathyroid gland adenomaprimary hyperparathyroidismsingle-photon emission computed tomographyultra-sonography

Identifiers

PMID36237812

DOI10.7759/cureus.29015

PMCPMC9551267

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