Evidence map›Paper›PMID 36237744›Full record

ReviewCureus2022

A Systematic Review Exploring the Effect of Human Immunodeficiency Virus on Cardiac Diseases.

Mohammed J Alzubaidee, Raga Sruthi Dwarampudi, Sheena Mathew, Sumahitha Bichenapally, Vahe Khachatryan, Asmaa Muazzam, Chandani Hamal, Lakshmi Sai Deepak Reddy Velugoti, Godfrey Tabowei, Greeshma N Gaddipati and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Mohammed J AlzubaideeInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Raga Sruthi DwarampudiResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sheena MathewPediatrics, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sumahitha BichenapallyInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Vahe KhachatryanInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Asmaa MuazzamPathology Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Chandani HamalInternal Medicine/Family Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Lakshmi Sai Deepak Reddy VelugotiResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Godfrey TaboweiInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Greeshma N GaddipatiResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Maria MukhtarInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Safeera KhanInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) primarily affects the immune systems, which, if progressed, will lead to acquired immunodeficiency syndrome (AIDS). Currently, there is no effective cure for the disease, and patients are affected lifelong, but there are antiretroviral medications that can control the disease's symptoms and progression. In addition, taking precautions during sexual contact, especially in the male homosexual population, while handling the patient's bodily fluids such as blood and saliva, and during childbirth by an infected mother is necessary to prevent the transmission of the virus. We used 15 studies, including systematic reviews and meta-analyses, observation studies, randomized clinical trials, and comprehensive reviews, to determine how HIV interferes with heart disease, increasing morbidity and mortality. We have used specific inclusion and exclusion criteria, focusing on specified age groups within a particular timeline. Some of the included studies found that many side effects from antiretroviral drugs can impact heart conditions, along with HIV, while others did not show a strong correlation between HIV and some heart diseases. In conclusion, after reviewing the literature, the results are inconclusive. More extensive trials focusing on the impact HIV has on heart disease are required to establish a strong correlation between HIV and heart disease to prevent morbidity and mortality.

Indexed as

heart diseaseheart failurehivhiv-associated lipodystrophy syndromehiv protease inhibitors

Identifiers

PMID36237744
PMCPMC9547769
OpenAlexW4295095774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.