Evidence map›Paper›PMID 36237732›Full record

ArticleACS omega2022

Assessing the Vulnerability of Cancer Patients for COVID-19.

Saloni Bhatia, Padmini Gokhale, Teesta Katte, Shreeshanthi Acharya, Avinash Arvind Rasalkar, Soumya Vidapanakal, Ram Manas, Sampath Chinnam, Prathibha Narayanan, Ashok Kumar Shettihalli and 2 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Saloni BhatiaDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Padmini GokhaleDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Teesta KatteDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Shreeshanthi AcharyaDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Avinash Arvind RasalkarPrabhat-Advanced Life Tech Solutions & Consultants, 4th Cross, Pharmacy College road, Sangolli Rayanna Nagar, Dharwad 580002, Karnataka, India.
Soumya VidapanakalDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Ram ManasDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Sampath ChinnamDepartment of Chemistry, M.S Ramaiah Institute of Technology (Affiliated to VTU), Bengaluru 560054, Karnataka, India.
Prathibha NarayananDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Ashok Kumar ShettihalliDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.
Vijayakumar KadappaDepartment of Computer Applications, B.M.S. College of Engineering, Bengaluru 560019, India.
Divijendra Natha Reddy SirigiriDepartment of Biotechnology, B.M.S. College of Engineering, Bull temple road, Bengaluru 560019, India.ORCID https://orcid.org/0000-0003-4657-2285
Bangalore Medical College and Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome involving corona virus-2 (SARS-CoV-2) has been implied to cause COVID-19 disease, leading to an unprecedented health emergency across the globe with a staggering figure of mortality rate. Measures to control the pandemic are pushing the economy into a tailspin, putting burden not only on the individuals but also on the nations. Despite the widespread infection rates, young people have shown better recovery rate while COVID-19 symptoms are more pronounced in elderly and people with comorbid conditions such as diabetes, cardiac and respiratory diseases. Cancer is a highly prevalent disease affecting millions of individuals. In this study, we analyzed the expression status of genes that are required for SARS-CoV-2 infectivity and its propagation to assess the susceptibility of certain cancer patients to infection and subsequent complications. Our data indicate that patients with colon, rectum, cholangiocarcinoma, lung adenoma, kidney renal papillary cell carcinoma and kidney renal clear cell carcinoma are more at risk for COVID-19. Genes that are responsible for severe COVID-19 are also highly expressed in many cancer types. We also carried out the association rule mining analysis which is helpful in predicting the expression of proviral genes in various cancers.

Identifiers

PMID36237732
PMCPMC9528021
OpenAlexW4298138685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.