ArticleFrontiers in neurology2022
Neuropsychiatric phenotype of post COVID-19 syndrome in non-hospitalized patients.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Meta-analysis of Cognitive Function Following Non-severe SARS-CoV-2 Infection.Neuropsychology review · 2025Pooled it
- The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Post-COVID neuropsychiatric symptoms in India: Prevalence, risk factors, and persistence.Indian journal of psychiatry · 2026Article
- The role of genetic liability for psychiatric disorders and personality traits in post covid syndrome: data from three Nordic population cohorts.EClinicalMedicine · 2026Article
- The effect of COVID-19 and socioeconomic inequalities on emergency department accesses for psychiatric conditions.PloS one · 2026Article
- Article
- Effects of an integrative multimodal inpatient program on fatigue and work ability in patients with Post-COVID Syndrome-a prospective observational study.European archives of psychiatry and clinical neuroscience · 2024Observational
- Substantial differences in perception of disease severity between post COVID-19 patients, internists, and psychiatrists or psychologists: the Health Perception Gap and its clinical implications.European archives of psychiatry and clinical neuroscience · 2024Article
- Is There such a Thing as Post-Viral Depression?: Implications for Precision Medicine.Biomolecules & therapeutics · 2024Review
- Self-reported immune status and COVID-19 associated subjective cognitive functioning in post-COVID-19 syndrome: Examination of an Irish cohort.Brain and behavior · 2024Article
- Three-Month Follow-Up of the Post-COVID Syndrome after Admission to a Specialised Post-COVID Centre-A Prospective Study Focusing on Mental Health with Patient Reported Outcome Measures (PROMs).International journal of environmental research and public health · 2024Article
- Psychological factors associated with Long COVID: a systematic review and meta-analysis.EClinicalMedicine · 2024Article
- Factors associated with cognitive impairment and the quality-of-life among COVID-19 survivors working as healthcare workers.Narra J · 2024Article
- Characteristic functional connectome related to Post-COVID-19 syndrome.Scientific reports · 2024Observational
- Clinical and serological predictors of post COVID-19 condition-findings from a Canadian prospective cohort study.Frontiers in public health · 2024Article
- The Impact of COVID-19 Lockdown Measures and COVID-19 Infection on Cognitive Functions: A Review in Healthy and Neurological Populations.International journal of environmental research and public health · 2023Review
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The post COVID-19 syndrome (PCS) is an emerging phenomenon worldwide with enormous socioeconomic impact. While many patients describe neuropsychiatric deficits, the symptoms are yet to be assessed and defined systematically. In this prospective cohort study, we report on the results of a neuropsychiatric consultation implemented in May 2021. A cohort of 105 consecutive patients with merely mild acute course of disease was identified by its high symptom load 6 months post infection using a standardized neurocognitive and psychiatric-psychosomatic assessment. In this cohort, we found a strong correlation between higher scores in questionnaires for fatigue (MFI-20), somatization (PHQ15) and depression (PHQ9) and worse functional outcome as measured by the post COVID functional scale (PCFS). In contrast, neurocognitive scales correlated with age, but not with PCFS. Standard laboratory and cardiopulmonary biomarkers did not differ between the group of patients with predominant neuropsychiatric symptoms and a control group of neuropsychiatrically unaffected PCS patients. Our study delineates a phenotype of PCS dominated by symptoms of fatigue, somatisation and depression. The strong association of psychiatric and psychosomatic symptoms with the PCFS warrants a systematic evaluation of psychosocial side effects of the pandemic itself and psychiatric comorbidities on the long-term outcome of patients with SARS-CoV-2 infection.
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