Evidence map›Paper›PMID 36237609›Full record

ArticleFrontiers in neurology2022

Autonomic dysfunction as the initial presentation in spinocerebellar ataxia type 3: A case report and review of the literature.

Yi Jin, Yuchao Chen, Dan Li, Mengqiu Qiu, Menglu Zhou, Zhouyao Hu, Qiusi Cai, Xulin Weng, Xiaodong Lu, Bin Wu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yi JinDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Yuchao ChenDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Dan LiDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Mengqiu QiuDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Menglu ZhouDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Zhouyao HuDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Qiusi CaiDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Xulin WengDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Xiaodong LuDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Bin WuDepartment of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Affiliated Hospital of Hangzhou Normal University · CNHangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinocerebellar ataxia type 3 (SCA3), as the most frequent autosomal dominant ataxia worldwide, is characterized by progressive cerebellar ataxia, dysarthria and extrapyramidal signs. Additionally, autonomic dysfunction, as a common clinical symptom, present in the later stage of SCA3. Here, we report a 44-year-old male patient with early feature of autonomic dysfunction includes hyperhidrosis and sexual dysfunction, followed by mild ataxia symptoms. The Unified Multiple System Atrophy Rating Scale (UMSARS) indicated significant dysautonomia during autonomic function testing. Combination of early and autonomic abnormalities and ataxia would be more characteristic of the cerebellar type of multiple system atrophy (MSA-C), the patient's positive family history and identification of an

Indexed as

autonomic dysfunctionearly stageinitial presentationsexual dysfunctionspinocerebellar ataxia type 3

Identifiers

PMID36237609
PMCPMC9552882
OpenAlexW4297370279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.