Evidence map›Paper›PMID 36237608›Full record

ArticleFrontiers in neurology2022

Flow diversion effect of the leo braided stent for aneurysms in the posterior and distal anterior circulations: A multicenter cohort study.

Yu Duan, Binbin Xu, Xuanfeng Qin, Renling Mao, Yuanyuan Hu, Bin Zhou, Jian Li, Gong Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Safety and efficacy of braided stents as stent monotherapy for the treatment of small intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yu DuanDepartments of Neurosurgery, Huadong Hospital, Fudan University, Shanghai, China.
Binbin XuDepartments of Neurosurgery, Shanghai Putuo District People's Hospital, Shanghai, China.
Xuanfeng QinDepartments of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Renling MaoDepartments of Neurosurgery, Huadong Hospital, Fudan University, Shanghai, China.
Yuanyuan HuDepartments of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Bin ZhouDepartments of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Jian LiDepartments of Neurosurgery, Huadong Hospital, Fudan University, Shanghai, China.
Gong ChenDepartments of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Fudan University · CNHuadong Hospital · CNHuashan Hospital · CNCentral Hospital of Putuo District · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: The treatment of aneurysms located in the posterior and distal anterior circulations remains a challenge. Leo stents with a flow diversion (FD) effect may be a potential option, which needs to be clearly studied. Methods: From January 2016 to October 2021, 133 patients with 145 aneurysms in the posterior and distal anterior circulations, treated with Leo stents, were retrospectively analyzed in three neurosurgical centers. Data on demographic information, aneurysm characteristics, procedural outcomes, postoperative course, and aneurysm occlusion were retrospectively analyzed. Results: After immediate surgery, 90 aneurysms (60.1%) were in complete occlusion [Raymond-Ray Occlusion Class (RROC) 1 and O'Kelly Marotta (OKM) grade D], 29 aneurysms (20%) in good occlusion (RROC 2 and OKM grade C), 17.9% in incomplete occlusion (RROC 3a or OKM grade B), and no aneurysms in invalid occlusion (RROC 3b and OKM grade A). A total of 112 patients with 117 aneurysms received angiographic follow-up (mean 11.4 months), and the degree of occlusion showed a significant improvement (Z = 3.900, Conclusions: Leo stents are safe and effective for aneurysms located in the posterior and distal anterior circulations. The overall degree of occlusion improved during a follow-up because of the FD effect of Leo stents. Aneurysms in these areas should be treated with personalized measures.

Indexed as

aneurysmendovascular treatmentflow diversionmulticenter studystents

Identifiers

PMID36237608
PMCPMC9551645
OpenAlexW4297312295

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.