Evidence map›Paper›PMID 36237287›Full record

ReviewBiomedical reports2022

Periodontitis, female fertility and conception (Review).

Elena Ricci, Simone Ciccarelli, Paola Agnese Mauri, Sandro Gerli, Alessandro Favilli, Sonia Cipriani, Francesco Fedele, Elena Roncella, Giovanna Esposito, Fabio Parazzini and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Biomedical reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Elena RicciDepartment of Clinical Sciences and Community Health, School of Medicine and Surgery, University of Milan, I-20122 Milan, Italy.
Simone CiccarelliDepartment of Clinical Sciences and Community Health, School of Medicine and Surgery, University of Milan, I-20122 Milan, Italy.
Paola Agnese MauriDepartment of Clinical Sciences and Community Health, School of Medicine and Surgery, University of Milan, I-20122 Milan, Italy.
Sandro GerliDepartment of Obstetrics and Gynecology, University of Perugia, S.M. Della Misericordia Hospital, I-06156 Perugia, Italy.
Alessandro FavilliDepartment of Obstetrics and Gynecology, University of Perugia, S.M. Della Misericordia Hospital, I-06156 Perugia, Italy.
Sonia CiprianiDepartment of Woman, Newborn and Child, Gynaecology Unit, 'Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico', I-20122 Milan, Italy.
Francesco FedeleDepartment of Clinical Sciences and Community Health, School of Medicine and Surgery, University of Milan, I-20122 Milan, Italy.
Elena RoncellaDepartment of Woman, Newborn and Child, Gynaecology Unit, 'Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico', I-20122 Milan, Italy.
Giovanna EspositoDepartment of Clinical Sciences and Community Health, School of Medicine and Surgery, University of Milan, I-20122 Milan, Italy.
Fabio ParazziniDepartment of Clinical Sciences and Community Health, School of Medicine and Surgery, University of Milan, I-20122 Milan, Italy.
Michele VignaliDepartment of Biomedical Sciences for Health, University of Milan, I-20133 Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease (PD) has been shown to increase the risk of preterm birth, preeclampsia and low birth weight. These observations have suggested that PD may also affect the early phase of pregnancy, including conception. The present study aimed to evaluate whether an association exists between oral health status and the chance of clinical pregnancy, according to the currently published literature, by performing a systematic review. The PubMed and EMBASE databases were searched from their start dates to October 2021 using the following keywords: 'Infertility' OR 'conception' OR 'pre-pregnancy' OR 'time-to-pregnancy' AND 'periodontitis' OR 'periodontal disease' OR 'dental infection' OR 'gingivitis' OR 'odontogenic infection' (limits: Full article, English, Human). A total of 6 papers reporting observational information on PD and spontaneous (4 studies) or medically induced conception (2 studies) were retrieved. As such, there were limited studies with different designs (randomized controlled trials and observational studies) and different settings. Moreover, in the selected studies, the ethnicity of the women was heterogeneous. According to the limited published literature, oral health might affect fertility in women. However, only results from prospective randomized trials, comparing PD treatment vs. no treatment in women seeking pregnancy, may clarify the real effectiveness of treatment in improving the conception rate.

Indexed as

conceptioninfertilityoral healthperiodontal diseasepregnancy

Identifiers

PMID36237287
PMCPMC9500491
OpenAlexW4295347097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.