Evidence map›Paper›PMID 36236328›Full record

ArticleSensors (Basel, Switzerland)2022

Near Infrared Emitting Semiconductor Polymer Dots for Bioimaging and Sensing.

Connor Riahin, Kushani Mendis, Brandon Busick, Marcin Ptaszek, Mengran Yang, Gary Stacey, Amar Parvate, James E Evans, Jeremiah Traeger, Dehong Hu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Connor RiahinDepartment of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, MD 21250, USA.ORCID 0000-0003-2353-2459
Kushani MendisDepartment of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
Brandon BusickDepartment of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
Marcin PtaszekDepartment of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, MD 21250, USA.ORCID 0000-0001-6468-6900
Mengran YangDivisions of Plant Sciences and Biochemistry, University of Missouri, Columbia, MO 65211, USA.
Gary StaceyDivisions of Plant Sciences and Biochemistry, University of Missouri, Columbia, MO 65211, USA.
Amar ParvateEnvironmental Molecular Sciences Laboratory (EMSL), Pacific Northwest National Laboratory, Richland, WA 99354, USA.ORCID 0000-0001-9282-5015
James E EvansEnvironmental Molecular Sciences Laboratory (EMSL), Pacific Northwest National Laboratory, Richland, WA 99354, USA.ORCID 0000-0002-7721-4782
Jeremiah TraegerEnvironmental Molecular Sciences Laboratory (EMSL), Pacific Northwest National Laboratory, Richland, WA 99354, USA.
Dehong HuEnvironmental Molecular Sciences Laboratory (EMSL), Pacific Northwest National Laboratory, Richland, WA 99354, USA.ORCID 0000-0002-3974-2963
Galya OrrEnvironmental Molecular Sciences Laboratory (EMSL), Pacific Northwest National Laboratory, Richland, WA 99354, USA.
Zeev RosenzweigDepartment of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, MD 21250, USA.ORCID 0000-0001-6098-3932
Pacific Northwest National Laboratory · USUniversity of Maryland, Baltimore County · USUniversity of Missouri · US

Funding

Graduate Training at The Chemistry Biology InterfaceT32GM066706 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SELEY-RADTKE, KATHERINE L, SMITH, AARON T · 2004 to 2023
$3.3M
NIGMS NIH HHS NIH/NIGMS T32 GM066706NIGMS NIH HHS T32 GM066706
6 · The paper itself

Abstract

Semiconducting polymer dots (Pdots) are rapidly becoming one of the most studied nanoparticles in fluorescence bioimaging and sensing. Their small size, high brightness, and resistance to photobleaching make them one of the most attractive fluorophores for fluorescence imaging and sensing applications. This paper highlights our recent advances in fluorescence bioimaging and sensing with nanoscale luminescent Pdots, specifically the use of organic dyes as dopant molecules to modify the optical properties of Pdots to enable deep red and near infrared fluorescence bioimaging applications and to impart sensitivity of dye doped Pdots towards selected analytes. Building on our earlier work, we report the formation of secondary antibody-conjugated Pdots and provide Cryo-TEM evidence for their formation. We demonstrate the selective targeting of the antibody-conjugated Pdots to FLAG-tagged FLS2 membrane receptors in genetically engineered plant leaf cells. We also report the formation of a new class of luminescent Pdots with emission wavelengths of around 1000 nm. Finally, we demonstrate the formation and utility of oxygen sensing Pdots in aqueous media.

Indexed as

PolymersQuantum DotsFluorescent DyesOxygenSemiconductorsFluorescent DyesOxygenPolymersnear infrared emissionplant cell imagingpolymer dotssensing

Identifiers

PMID36236328
PMCPMC9571013
OpenAlexW4297238349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.