Evidence map›Paper›PMID 36236066›Full record

ArticlePolymers2022

3D-Printed PLA Medical Devices: Physicochemical Changes and Biological Response after Sterilisation Treatments.

Sara Pérez-Davila, Laura González-Rodríguez, Raquel Lama, Miriam López-Álvarez, Ana Leite Oliveira, Julia Serra, Beatriz Novoa, Antonio Figueras, Pío González

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sara Pérez-DavilaCINTECX, Universidade de Vigo, Grupo de Novos Materiais, 36310 Vigo, Spain.ORCID 0000-0001-7694-3847
Laura González-RodríguezCINTECX, Universidade de Vigo, Grupo de Novos Materiais, 36310 Vigo, Spain.
Raquel LamaInstitute of Marine Research (IIM), National Research Council (CSIC), 36208 Vigo, Spain.ORCID 0000-0003-4976-926X
Miriam López-ÁlvarezCINTECX, Universidade de Vigo, Grupo de Novos Materiais, 36310 Vigo, Spain.ORCID 0000-0003-0118-7412
Ana Leite OliveiraUniversidade Católica Portuguesa, CBQF-Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo de Botelho, 1327, 4169-005 Porto, Portugal.
Julia SerraCINTECX, Universidade de Vigo, Grupo de Novos Materiais, 36310 Vigo, Spain.ORCID 0000-0001-6187-4025
Beatriz NovoaInstitute of Marine Research (IIM), National Research Council (CSIC), 36208 Vigo, Spain.ORCID 0000-0003-4888-8419
Antonio FiguerasInstitute of Marine Research (IIM), National Research Council (CSIC), 36208 Vigo, Spain.ORCID 0000-0002-0617-0030
Pío GonzálezCINTECX, Universidade de Vigo, Grupo de Novos Materiais, 36310 Vigo, Spain.ORCID 0000-0002-7353-712X
Galicia Sur Biomedical Foundation · ESInstituto de Investigacións Mariñas · ESUniversidade Católica Portuguesa · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polylactic acid (PLA) has become one of the most commonly used polymers in medical devices given its biocompatible, biodegradable and bioabsorbable properties. In addition, due to PLA's thermoplastic behaviour, these medical devices are now obtained using 3D printing technologies. Once obtained, the 3D-printed PLA devices undergo different sterilisation procedures, which are essential to prevent infections. This work was an in-depth study of the physicochemical changes caused by novel and conventional sterilisation techniques on 3D-printed PLA and their impact on the biological response in terms of toxicity. The 3D-printed PLA physicochemical (XPS, FTIR, DSC, XRD) and mechanical properties as well as the hydrophilic degree were evaluated after sterilisation using saturated steam (SS), low temperature steam with formaldehyde (LTSF), gamma irradiation (GR), hydrogen peroxide gas plasma (HPGP) and CO

Indexed as

3D printingbiological responsemedical devicesphysicochemical changespolylactic acid (PLA)sterilisationzebrafish model

Identifiers

PMID36236066
PMCPMC9572917
OpenAlexW4303980908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.