Evidence map›Paper›PMID 36235958›Full record

ArticlePolymers2022

Ultrasonic Film Rehydration Synthesis of Mixed Polylactide Micelles for Enzyme-Resistant Drug Delivery Nanovehicles.

Darya A Stepanova, Vladislava A Pigareva, Anna K Berkovich, Anastasia V Bolshakova, Vasiliy V Spiridonov, Irina D Grozdova, Andrey V Sybachin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Darya A StepanovaLeninskie Gory, 1-3, Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
Vladislava A PigarevaLeninskie Gory, 1-3, Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-3989-2232
Anna K BerkovichLeninskie Gory, 1-3, Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
Anastasia V BolshakovaLeninskie Gory, 1-3, Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
Vasiliy V SpiridonovLeninskie Gory, 1-3, Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
Irina D GrozdovaLeninskie Gory, 1-3, Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
Andrey V SybachinLeninskie Gory, 1-3, Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-4860-5565

Funding

Russian Science Foundation 22-23-00723
6 · The paper itself

Abstract

A facile technique for the preparation of mixed polylactide micelles from amorphous poly-D,L-lactide-block-polyethyleneglycol and crystalline amino-terminated poly-L-lactide is described. In comparison to the classical routine solvent substitution method, the ultrasonication assisted formation of polymer micelles allows shortening of the preparation time from several days to 15-20 min. The structure and morphology of mixed micelles were analyzed with the assistance of electron microscopy, dynamic and static light scattering and differential scanning calorimetery. The resulting polymer micelles have a hydrodynamic radius of about 150 nm and a narrow size distribution. The average molecular weight of micelles was found to be 2.1 × 10

Indexed as

cytotoxicitydrug deliverypaclitaxelPaclitaxel-Tevapolylactidepolylactide micellesself-assemblysynthesistaxolultrasonication

Identifiers

PMID36235958
PMCPMC9571646

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.