Evidence map›Paper›PMID 36235952›Full record

ArticlePolymers2022

L-Cysteine Modified Chitosan Nanoparticles and Carbon-Based Nanostructures for the Intranasal Delivery of Galantamine.

Stavroula G Nanaki, Konstantinos Spyrou, Pelagia Veneti, Niki Karouta, Dimitrios Gournis, Turki N Baroud, Panagiotis Barmpalexis, Dimitrios N Bikiaris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Stavroula G NanakiLaboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Konstantinos SpyrouDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-2032-8439
Pelagia VenetiLaboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Niki KaroutaDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.
Dimitrios GournisDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.
Turki N BaroudMaterials Science and Engineering, King Fahd University of Petroleum & Minerals, Dhahran 31261, Saudi Arabia.ORCID 0000-0001-6430-9128
Panagiotis BarmpalexisDepartment of Pharmaceutical Technology, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-6765-512X
Dimitrios N BikiarisLaboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-8458-4952
Aristotle University of Thessaloniki · GRUniversity of Ioannina · GRKing Fahd University of Petroleum and Minerals · SA

Funding

This project has received funding from the Hellenic Foundation for Research and Innovation (HFRI) and the General Secretariat for Research and Technology (GSRT), under grant agreement No [1914]. 1914
6 · The paper itself

Abstract

The present study evaluates the use of thiolized chitosan conjugates (CS) in combination with two fundamental carbon nanoforms (carbon dots (CDs) and Hierarchical Porous Carbons (HPC)) for the preparation of intranasally (IN) administrated galantamine (GAL) nanoparticles (NPs). Initially, the modification of CS with L-cysteine (Cys) was performed, and the successful formation of a Cys-CS conjugates was verified via

Indexed as

carbon dotsdrug deliverygalantamineL-cysteinemodified chitosannanoparticlesporous carbon nanostructures

Identifiers

PMID36235952
PMCPMC9571213
OpenAlexW4297238246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.