Evidence map›Paper›PMID 36235822›Full record

ArticleNutrients2022

Mulberrofuran G, a Mulberry Component, Prevents SARS-CoV-2 Infection by Blocking the Interaction between SARS-CoV-2 Spike Protein S1 Receptor-Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor.

Young Soo Kim, Buyun Kim, Eun-Bin Kwon, Hwan-Suck Chung, Jang-Gi Choi

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Young Soo KimKorean Medicine Application Center, Korea Institute of Oriental Medicine, Dong-gu, Daegu 41062, Korea.ORCID 0000-0003-0605-1231
Buyun KimKorean Medicine Application Center, Korea Institute of Oriental Medicine, Dong-gu, Daegu 41062, Korea.
Eun-Bin KwonKorean Medicine Application Center, Korea Institute of Oriental Medicine, Dong-gu, Daegu 41062, Korea.
Hwan-Suck ChungKorean Medicine Application Center, Korea Institute of Oriental Medicine, Dong-gu, Daegu 41062, Korea.ORCID 0000-0002-5901-0217
Jang-Gi ChoiKorean Medicine Application Center, Korea Institute of Oriental Medicine, Dong-gu, Daegu 41062, Korea.
Korea Institute of Oriental Medicine · KR

Funding

Ministry of Science and ICT (Korea Institute of Oriental Medicine) KSN2022230Ministry of Science and ICT (the National Research Foundation of Korea) NSN2211130
6 · The paper itself

Abstract

Despite the recent development of RNA replication-targeted COVID-19 drugs by global pharmaceutical companies, their prescription in clinical practice is limited by certain factors, including drug interaction, reproductive toxicity, and drug resistance. COVID-19 drugs with multiple targets for the SARS-CoV-2 life cycle may lead to a successful reduction in drug resistance as well as enhanced therapeutic efficacy, and natural products are a potential source of molecules with therapeutic effects against COVID-19. In this study, we investigated the inhibitory efficacy of mulberrofuran G (MG), a component of

Indexed as

Biological ProductsCOVID-19 Drug TreatmentMorusAngiotensin-Converting Enzyme 2BenzofuransHumansPeptidyl-Dipeptidase ASARS-CoV-2Spike Glycoprotein, CoronavirusTerpenesAngiotensin-Converting Enzyme 2BenzofuransBiological Productsmulberrofuran GPeptidyl-Dipeptidase ASpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2TerpenesACE2 receptorcoronavirus disease 2019mulberrofuran Gmulberrysevere acute respiratory syndrome coronavirus 2spike protein

Identifiers

PMID36235822
PMCPMC9573737
OpenAlexW4303961798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.