ArticleNutrients2022
Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007-2018.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- The Relationship Between Trace Elements and Depression.Nutrients · 2026Review
- Associations of multiple trace elements with bipolar disorder in adolescents: A case-control study.PloS one · 2025Article
- Relationship between oxidative balance score and risk of sleep-related problems.Frontiers in nutrition · 2025Article
- Depressed mood affects the process of biological aging, analyses from the NHANES dataset.Frontiers in aging · 2025Review
- Dietary protein intake affects the association between urinary iodine and clinically relevant depression: Evidence from NHANES 2007-2018.Food science & nutrition · 2023Article
- Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone.Nutrients · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between iodine status and depressive symptoms has not been investigated in the general population. Therefore, we drew 8935 participants from the National Health and Nutrition Examination Survey (NHANES) 2007-2018 to explore their association. In NHANES, Inductively Coupled Plasma Dynamic Reaction Cell Mass Spectroscopy was utilized to measure urinary iodine concentration (UIC), and Patient Health Questionnaire-9 was used to assess depressive symptoms. Meanwhile, we fitted logistic regression and restricted cubic spline models. We found that high UIC was associated with a higher prevalence of depressive symptoms than the normal UIC group (OR: 1.50, 95% CI: 1.04-2.16). This association was particularly pronounced and further strengthened among females (OR: 1.90, 95% CI: 1.19-3.01) and participants aged 40-59 (OR: 1.90, 95% CI: 1.11-3.25). Moreover, we found that low UIC was associated with a high prevalence of depressive symptoms among females (OR: 1.50, 95% CI: 1.02-2.18). Moreover, the dose-response relationship between UIC and depressive symptoms presented a general trend of decreased, steady transiently, and then increased. We found that participants with high UIC had a higher prevalence of depressive symptoms than those with normal UIC. Meanwhile, we also found that females with low UIC had higher odds of reporting depressive symptoms.
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