Evidence map›Paper›PMID 36235815›Full record

ArticleNutrients2022

Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study.

Thaís Barros Pereira da Silva, Mariane Marques Luiz, Maicon Luís Bicigo Delinocente, Andrew Steptoe, Cesar de Oliveira, Tiago da Silva Alexandre

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Thaís Barros Pereira da SilvaDepartment of Gerontology, Federal University of São Carlos, Rodovia Washington Luís, Km 235, SP-310, São Carlos 13565-905, São Paulo, Brazil.ORCID 0000-0001-8554-8638
Mariane Marques LuizPostgraduate Program in Physical Therapy, Federal University of São Carlos, Rodovia Washington Luís, Km 235, SP-310, São Carlos 13565-905, São Paulo, Brazil.ORCID 0000-0001-5563-6354
Maicon Luís Bicigo DelinocentePostgraduate Program in Gerontology, Federal University of São Carlos, Rodovia Washington Luís, Km 235, SP-310, São Carlos 13565-905, São Paulo, Brazil.
Andrew SteptoeDepartment of Epidemiology and Public Health, University College London, Gower Street, London WC1E 6BT, UK.
Cesar de OliveiraDepartment of Epidemiology and Public Health, University College London, Gower Street, London WC1E 6BT, UK.ORCID 0000-0002-4099-4762
Tiago da Silva AlexandreDepartment of Gerontology, Federal University of São Carlos, Rodovia Washington Luís, Km 235, SP-310, São Carlos 13565-905, São Paulo, Brazil.ORCID 0000-0003-3791-9793
Universidade Federal de São Carlos · BRUniversity College London · GB

Funding

Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
Coordination for the Improvement of Higher Education Personnel - Institutional International-ization Program (CAPES-PrInt) 88887.570076/2020-00Economic and Social Research Council (ESRC) ES/T008822/11National Council of Scientific and Technological Development (CNPq) 303577/2020-7National Council of Scientific and Technological Development (CNPq) 303981/2017-2National Institute on Aging USA R01AG017644NIA NIH HHS R01 AG017644Sao Paulo Research Foundation (FAPESP) 2018/13917-3Sao Paulo Research Foundation (FAPESP) 2020/06716-1
6 · The paper itself

Abstract

Cross-sectional studies have demonstrated an association between abdominal obesity, determined by waist circumference (WC), and vitamin D (25(OH)D) deficiency in older adults. However, longitudinal evidence is based only on general obesity determined using body mass index (BMI). We investigated whether abdominal obesity is associated with the incidence of 25(OH)D insufficiency (>30 and ≤50 nmol/L) and deficiency (≤30 nmol/L), and whether vitamin D supplementation modifies these associations. We included 2459 participants aged ≥50 years from the English Longitudinal Study of Ageing (ELSA) with 25(OH)D sufficiency (>50 nmol/L) at baseline. Abdominal obesity was defined as >88 cm for women and >102 cm for men. After 4 years, 25(OH)D concentrations were reassessed. Multinomial logistic regression models controlled by covariates were performed. Abdominal obesity increased the risk of the incidence of 25(OH)D insufficiency (RRR = 1.36; 95% CI: 1.01−1.83) and deficiency (RRR = 1.64; 95% CI: 1.05−2.58). These risks were maintained when excluding individuals who took vitamin D supplementation (RRR = 1.38; 95% CI: 1.02−1.88) and (RRR = 1.62; 95% CI: 1.02−2.56). Abdominal obesity is associated with the risk of incidence of low 25(OH)D concentrations. WC seems to be an adequate tool for screening individuals with obesity and at potential risk of developing these conditions.

Indexed as

Vitamin DVitamin D DeficiencyAgedBody Mass IndexCross-Sectional StudiesFemaleHumansIncidenceLongitudinal StudiesMaleObesityObesity, AbdominalRisk FactorsVitaminsVitamin DVitamins25(OH)Dabdominal obesityagingincidencevitamin Dwaist circumference

Identifiers

PMID36235815
PMCPMC9572900
OpenAlexW4303962075

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.