Evidence map›Paper›PMID 36235776›Full record

SynthesisNutrients2022

Vitamin D-Related Risk Factors for Maternal Morbidity and Mortality during Pregnancy: Systematic Review and Meta-Analysis.

María Morales-Suárez-Varela, Nazlı Uçar, José Miguel Soriano, Agustín Llopis-Morales, Beth S Sanford, William B Grant

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Association betweenPeerJ · 2023
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María Morales-Suárez-VarelaArea of Preventive Medicine and Public Health, Department of Preventive Medicine and Public Health, Food Sciences, Toxicology, and Legal Medicine, School of Pharmacy, University de Valencia, 46100 Burjassot, Spain.ORCID 0000-0003-0785-1492
Nazlı UçarArea of Preventive Medicine and Public Health, Department of Preventive Medicine and Public Health, Food Sciences, Toxicology, and Legal Medicine, School of Pharmacy, University de Valencia, 46100 Burjassot, Spain.ORCID 0000-0003-2878-5519
José Miguel SorianoFood & Health Lab, Institute of Materials Science, University of Valencia, 46980 Paterna, Spain.
Agustín Llopis-MoralesArea of Preventive Medicine and Public Health, Department of Preventive Medicine and Public Health, Food Sciences, Toxicology, and Legal Medicine, School of Pharmacy, University de Valencia, 46100 Burjassot, Spain.
Beth S SanfordCollege of Nursing, Rasmussen University, 4012 19th Ave S, Fargo, ND 58103, USA.
William B GrantSunlight, Nutrition, and Health Research Center, P.O. Box 641603, San Francisco, CA 94164, USA.ORCID 0000-0002-1439-3285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D deficiency (serum 25-hydroxyvitamin D [25(OH)D] levels <20 ng/mL in serum) is a common health condition among pregnant women, especially in high-risk groups. Evidence has connected vitamin D levels with many health-related problems during pregnancy, including gestational diabetes and preeclampsia. Because of vitamin D’s effect on both mother and fetus, we systematically review the association between 25(OH)D level and its health effects. From a total of 143 studies, 43 came from PubMed, 4 from Cochrane, and 96 from EMBASE. After screening, we identified 38 studies as candidates for inclusion. Ultimately, we limited this review to 23 articles originating from 12 countries, written in English or Spanish, and conducted between 2010 and 2022. We conducted this review according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines and evaluated the quality and strength of the evidence by using the Navigation Guide Systematic Review Methodology (SING). These systematic reviews summarize findings that support vitamin D’s role in reducing risks of multiple outcomes and the possible contribution of adequate vitamin D levels to a healthy pregnancy.

Indexed as

Pregnancy ComplicationsVitamin D DeficiencyFemaleHumansPregnancyPregnancy OutcomeRisk FactorsVitamin DVitaminsVitamin DVitamins25-hydroxyvitamin Dmaternal morbiditymaternal mortalitypreeclampsiapregnancysupplementationvitamin Dvitamin D deficiency

Identifiers

PMID36235776
PMCPMC9572094

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.