Dietary Restriction against Parkinson's Disease: What We Know So Far.

Zhonglei Wang, Yueran Cui, Lulu Wen, Haiyang Yu, Juan Feng, Wei Yuan, Xin He

Abstract readReview

In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhonglei WangDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

Yueran CuiDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

Lulu WenDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

Haiyang YuDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

Juan FengDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

Wei YuanDepartment of Orthopedics, The First Hospital of China Medical University, Shenyang 110001, China.

Xin HeDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

Funding

Xin He A435

6 · The paper itself

Abstract

Dietary restriction (DR) is defined as a moderate reduction in food intake while avoiding malnutrition. The beneficial effects of DR are being increasingly acknowledged in aging and in a series of age-related neurodegenerative disorders, for example, Parkinson's disease (PD). To date, the pathogenesis of PD remains elusive and there is no cure for it in spite of intensive research over decades. In this review, we summarize the current knowledge on the efficacy of DR on PD, focusing on the underlying mechanisms involving general metabolism, neuroendocrinolgy, neuroinflammation, gut microbiome, and so on. We anticipate that this review will provide future perspectives for PD prevention and treatment.

Indexed as

Gastrointestinal MicrobiomeNeurodegenerative DiseasesParkinson DiseaseAgingHumansdietary restrictiongut microbiomemechanismParkinson’s diseasepatientspreventiontreatment

Identifiers

PMID36235760

DOI10.3390/nu14194108

PMCPMC9571011

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.