ArticleNutrients2022
Association of Visceral Fat Area and Hyperuricemia in Non-Obese US Adults: A Cross-Sectional Study.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Threshold effect of the METS-VF index on hyperuricemia in adults with hypertension: a cross-sectional study.BMC endocrine disorders · 2026Article
- Correlation of skeletal muscle mass and visceral fat area with hyperuricemia in male adolescents.BMC endocrine disorders · 2026Article
- Association between the triglyceride-glucose index and hyperuricemia in an apparently healthy population with zero metabolic syndrome components: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Article
- Association of LDL-C/HDL-C Ratio With Hyperuricemia: A National Cohort Study.Clinical and translational science · 2025Article
- Systemic immunity-inflammation index is associated with body fat distribution among U.S. adults: evidence from national health and nutrition examination survey 2011-2018.BMC endocrine disorders · 2024Article
- Research progress on bariatric surgery for hyperuricemia.BMC surgery · 2024Review
- L-shaped association between lean body mass to visceral fat mass ratio with hyperuricemia: a cross-sectional study.Lipids in health and disease · 2024Article
- The agreement of low lean mass with obesity using different definitions and its correlation with hyperuricemia.Frontiers in nutrition · 2024Article
- Exploring the Relationship Between Different Obesity Metabolism Indices and Hyperuricemia in Patients with Hypertension and Coronary Heart Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Association between serum carotenoids and hyperuricemia: a cross-sectional study based on NHANES 2001-2006.Frontiers in nutrition · 2024Article
- The Interplay of Systemic Inflammation and Oxidative Stress in Connecting Perirenal Adipose Tissue to Hyperuricemia in Type 2 Diabetes Mellitus: A Mediation Analysis.Journal of inflammation research · 2024Article
- The association of visceral fat metabolism score with hyperuricemia-evidence from NHANES 1999-2018.Frontiers in nutrition · 2024Article
- A comprehensive analysis of erectile dysfunction prevalence and the impact of prostate conditions on ED among US adults: evidence from NHANES 2001-2004.Frontiers in endocrinology · 2024Observational
- The Association of Food Groups and Consumption Time with Hyperuricemia: The U.S. National Health and Nutrition Examination Survey, 2005-2018.Nutrients · 2023Article
- Association between urinary albumin-to-creatinine ratio within normal range and hypertension among adults in the United States: Data from the NHANES 2009-2018.Clinical cardiology · 2023Article
- A cross-sectional study on the association between dietary inflammatory index and hyperuricemia based on NHANES 2005-2018.Frontiers in nutrition · 2023Article
- Association of serum uric acid Levels with metabolic syndromes in Korean adolescents.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate the relationship between visceral fat area (VFA) and hyperuricemia (HUA) among non-obese adults. We extracted data from 6224 US adults aged 20−59 years from the National Health and Nutrition Examination Survey (NHANES) from 2011−2018. The VFA was divided into four quartiles (Q1−Q4). We used multivariable logistic regression models to control for known confounders. A generalized additive model (GAM) and restricted cubic spines were used to examine the association between VFA and HUA stratified by sex, and a two-piecewise linear regression model was used to calculate the threshold effect among males. The results revealed that the prevalence of HUA was 11.8% (men 15.8%, women 7.2%). In the fully adjusted model, there was a positive association between VFA and HUA [as a quartile variable, Q4 vs. Q1, odds ratio (OR): 3.77 and 95% confidence interval (CI): (2.47~5.75), p < 0.001, p for trend < 0.001; as a continuous variable, per 10 cm2 increment, OR (95%CI):1.10(1.07,1.14), p < 0.001]. Besides, this positive association remained significantly stratified by sex. Interestingly, we observed a nonlinear dose-response relationship between VFA and HUA in males (inflection point: 107.46 cm2). In conclusion, our study confirmed a significant positive relationship between VFA and HUA among non-obese adults and remained statistically significant when stratified by sex.
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