Evidence map›Paper›PMID 36235583›Full record

ArticleNutrients2022

Minhong Ren, Meng-Yun Li, Lin-Qian Lu, Yuan-Sen Liu, Feng-Kun An, Kai Huang, Zhen Fu

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Minhong RenGuangxi Vocational & Technical Institute of Industry, Nanning 530001, China.ORCID 0000-0002-4008-0995
Meng-Yun LiCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China.
Lin-Qian LuCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China.
Yuan-Sen LiuCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China.
Feng-Kun AnCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China.
Kai HuangGuangxi Vocational & Technical Institute of Industry, Nanning 530001, China.
Zhen FuCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China.ORCID 0000-0001-9404-8707
Guangxi University · CNGuangxi Research Institute of Chemical Industry · CN

Funding

Natural Science Foundation of Guangxi Province 2018CXNSFAA050143Natural Science Foundation of Guangxi Province 2019GXNSFAA185014
6 · The paper itself

Abstract

This study aimed to compare the regulatory effects of Arenga pinnata retrograded starch (APRS), Arenga pinnata starch (APS), and whole Arenga pinnata flour (APF) on gut microbiota and improvement of intestinal inflammation in aged mice. APF, APS, and APRS altered gut microbiota composition and exhibited different prebiotic effects. Bifidobacterium showed the greatest increase in feces of aged mice fed APF. The abundance of genus Lachnospiraceae_NK4A136 was highest in the APS group. APRS supplementation led to a greatest increasement in abundance of Lactobacillus, Roseburia, and Faecalibacterium prausnitzii. APRS induced significantly more short-chain fatty acid (SCFAs) production than APF and APS. APF, APS, and APRS treatments improved intestinal inflammation in aged mice and the order of ameliorative effect was APRS > APS > APF. APRS significantly decreased relative mRNA expression of pro-inflammatory cytokines (IL-6, IL-1β, and TNF-α) and increased anti-inflammatory cytokines (IL-10). In addition, APF, APS, and APRS significantly downregulated the relative mRNA expression of senescence-associated gene p53 and upregulated the expression of anti-aging gene Sirt1. These results provide potentially useful information about the beneficial effects of Arenga pinnata products on human health.

Indexed as

ArecaceaeGastrointestinal MicrobiomeAnimalsAnti-Inflammatory AgentsCytokinesFatty Acids, VolatileInflammationInterleukin-10Interleukin-6MiceResistant StarchRNA, MessengerSirtuin 1StarchTumor Necrosis Factor-alphaTumor Suppressor Protein p53Anti-Inflammatory AgentsCytokinesFatty Acids, VolatileInterleukin-10Interleukin-6Resistant StarchRNA, MessengerSirtuin 1StarchTumor Necrosis Factor-alphaTumor Suppressor Protein p53Arenga pinnatagut microbiotaresistant starch

Identifiers

PMID36235583
PMCPMC9572357
OpenAlexW4296641961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.