ReviewPlants (Basel, Switzerland)2022
Bioactivity and Therapeutic Potential of Kaempferol and Quercetin: New Insights for Plant and Human Health.
Review in Plants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 1 synthesis or guideline pooled it, 208 citations in OpenAlex.
- Bibliometric and visual analysis of global publications on kaempferol.Frontiers in nutrition · 2024Pooled it
- Identification of potential flavonoids strongly correlated with bitterness and astringency in quinoa seedling vegetables via metabolomics and electronic tongue.Food chemistry: X · 2026Article
- Comparative Biochemistry of Wild and In Vitro-PropagatedLife (Basel, Switzerland) · 2026Article
- Comparative Analysis of Phenolic Acid Profiles, Antioxidant Capacity, and Antimicrobial Activity of Honeys from Different Botanical and Geographical Origins.International journal of molecular sciences · 2026Article
- Kaempferol: advances in biosynthesis, molecular mechanisms, and therapeutic applications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Regulatory Roles of Kaempferol on the PI3K/AKT/mTOR Signaling Pathway and Associated MicroRNAs in Different Cancer Types.International journal of molecular sciences · 2026Review
- Biostimulatory Effect of 3-Acetonyl-3-Hydroxyoxindole on the Growth and Secondary Metabolites ofInternational journal of molecular sciences · 2026Article
- Evaluating the Safety of Ashwagandha as a Food Additive: A Focus on Reproductive, Thyroid, and Immune System Effects.Phytotherapy research : PTR · 2026Review
- Integrated Chemical Profiling and Biological Assessment ofAntibiotics (Basel, Switzerland) · 2026Article
- Species-Specific Metabolic Identities Persist in Fabaceae Callus Cultures Under Standardized Culture Conditions.Plants (Basel, Switzerland) · 2026Article
- Multi-Target Bioactivity ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Comparative Analysis of Oligosaccharide and Phenolic Profiles in White and Red Grape Pomace from California.Molecules (Basel, Switzerland) · 2026Article
- Effects of plant flavonoids and selenium on pancreatic hormones and glucose homeostasis in autoimmune thyroiditis.Experimental animals · 2026Article
- Potential Health Benefits of Bee Bread from Stingless Bees on Reproductive Health: A Review.International journal of molecular sciences · 2026Review
- Kombucha-Mediated Fermentation Enhances Antioxidant, Anti-Inflammatory, Anti-Ageing and Antimicrobial Properties of Fruit Tree Leaf Agro-Waste Extracts fromInternational journal of molecular sciences · 2026Article
- Exploring the Chemical Profile and Biological Activities ofMolecules (Basel, Switzerland) · 2026Article
- Kaempferol-based nanocarriers as a potential therapeutic strategy against drug-resistant lung cancer.Cancer cell international · 2026Review
- Comparative Phytochemical Profiling and In Vitro Investigation of the Antioxidant and Antimicrobial Potential ofMolecules (Basel, Switzerland) · 2026Article
- Flavonoids as Dual Topoisomerase I and II Inhibitors: Mechanistic Insights and Emerging Anticancer Strategies.Chemistry & biodiversity · 2026Review
- Effect of Drying and Cooking on the Chemical Composition, Phenolic Profile, and Antioxidant Capacity ofPlants (Basel, Switzerland) · 2026Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant secondary metabolites, especially flavonoids, are major metabolites widely found in plants that play several key roles in plant defence and signalling in response to stress conditions. The most studied among these flavonoids are kaempferol and quercetin due to their anti-oxidative potential and their key roles in the defence system, making them more critical for plant adaptation in stress environments. Kaempferol and quercetin in plants have great therapeutic potential for human health. Despite being well-studied, some of their functional aspects regarding plants and human health need further evaluation. This review summarizes the emerging potential of kaempferol and quercetin in terms of antimicrobial activity, bioavailability and bioactivity in the human body as well as in the regulation of plant defence in response to stresses and as a signalling molecule in terms of hormonal modulation under stress conditions. We also evaluated the safe use of both metabolites in the pharmaceutical industry.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.