ArticleMolecules (Basel, Switzerland)2022
Preparation, Characterization and Biological Activities of an Oil-in-Water Nanoemulsion from Fish By-Products and Lemon Oil by Ultrasonication Method.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Ultrasonication-Enhanced Physicochemical Stability and Antimicrobial Efficacy of Zein-Based Nanomaterials Loaded With Cinnamaldehyde and D-Limonene.Journal of food science · 2026Article
- Enhancing the anticancer potential of garlic and lemon essential oils through nanoemulsification: a comparative study.Scientific reports · 2026Article
- From Fish Waste to Stable Omega-3 Bioactive Lipids: Encapsulation Strategies and a Conceptual Framework for Antioxidant and Antimicrobial Functional Food Fortification.Food science & nutrition · 2026Review
- Cutaneous delivery of bioactive components from a rice bran oil nanoemulsion and their biodistribution in porcine and human skin.International journal of pharmaceutics: X · 2026Article
- Rheological Characterization of Lemon Oil-Loaded Eucerin Cream and Aquaphor Ointment.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Solubility prediction and cytotoxicity of lipidic microemulsion: HSPiP modeling and synergism with ciclopirox olamine.Scientific reports · 2025Article
- Comparative Stability and Anesthetic Evaluation of Holy Basil Essential Oil Formulated in SNEDDS and Microemulsion Systems inPharmaceutics · 2025Article
- Supercritical COFood technology and biotechnology · 2024Article
- Current Trends in Food Processing By-Products as Sources of High Value-Added Compounds in Food Fortification.Foods (Basel, Switzerland) · 2024Review
- Green Synthesis ofMolecules (Basel, Switzerland) · 2024Article
- Flavonoid Extracts from Lemon By-Products as a Functional Ingredient for New Foods: A Systematic Review.Foods (Basel, Switzerland) · 2023Review
- Fabrication and Biological Activities of All-in-One Composite Nanoemulsion Based onMolecules (Basel, Switzerland) · 2023Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Fish by-product oil and lemon oil have potential applications as active ingredients in many industries, including cosmetics, pharmaceuticals and food. However, the physicochemical properties, especially the poor stability, compromised the usage. Generally, nanoemulsions were used as an approach to stabilize the oils. This study employed an ultrasonication method to form oil-in-water nanoemulsion of lemon and fish by-product oils (NE-FLO). The formulation is produced at a fixed amount of 2 wt% fish by-product oil, 8 wt% lemon oil, 10 wt% surfactant, 27.7 wt% co-surfactants and 42 min of ultrasonication time. The size, polydispersity index (PDI) and zeta potential obtained were 44.40 nm, 0.077, and -5.02 mV, respectively. The biological properties, including antioxidant, antibacterial, cell cytotoxicity, and anti-inflammatory, showed outstanding performance. The antioxidant activity is comparable without any significant difference with ascorbic acid as standard and is superior to pure lemon oil. NE-FLO successfully inhibits seven Gram-positive and seven Gram-negative bacterial strains. NE-FLO's anti-inflammatory activity is 99.72%, comparable to nordihydroguaiaretic acid (NDGA) as the standard. At a high concentration of 10,000 µg·mL
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