Evidence map›Paper›PMID 36235241›Full record

ArticleMolecules (Basel, Switzerland)2022

Effects of the Seed Oil of

Lidiani Figueiredo Santana, Bruna Larissa Spontoni do Espirito Santo, Mariana Bento Tatara, Fábio Juliano Negrão, Júlio Croda, Flávio Macedo Alves, Wander Fernando de Oliveira Filiú, Leandro Fontoura Cavalheiro, Carlos Eduardo Domingues Nazário, Marcel Arakaki Asato and 5 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. High-Value Compounds in Papaya By-Products (Plants (Basel, Switzerland) · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Lidiani Figueiredo SantanaGraduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.ORCID 0000-0001-9171-4698
Bruna Larissa Spontoni do Espirito SantoGraduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.
Mariana Bento TataraHealth Science Research Laboratory, Federal University of Grande Dourados, Dourados 79804-970, Brazil.
Fábio Juliano NegrãoHealth Science Research Laboratory, Federal University of Grande Dourados, Dourados 79804-970, Brazil.
Júlio CrodaOswaldo Cruz Foundation, Campo Grande 79074-460, Brazil.
Flávio Macedo AlvesLaboratory of Botany, Institute of Biosciences, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.ORCID 0000-0001-5634-8266
Wander Fernando de Oliveira FiliúFaculty of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79079-900, Brazil.
Leandro Fontoura CavalheiroChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Carlos Eduardo Domingues NazárioChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Marcel Arakaki AsatoMedical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Bernardo Bacelar de FariaDiagnostic Medicine Laboratory-Scapulatempo, Campo Grande 79002-17, Brazil.
Valter Aragão do NascimentoGraduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.ORCID 0000-0002-9020-8002
Rita de Cássia Avellaneda GuimarãesGraduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.
Karine de Cássia FreitasGraduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.
Priscila Aiko HianeGraduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.ORCID 0000-0003-1115-4083
Universidade Federal de Mato Grosso do Sul · BRUniversidade Federal da Grande Dourados · BRFundação Oswaldo Cruz · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

backgroundStudies indicate that different parts of

methodsThe fatty acid composition of the oil extracted from the seeds of

resultsPapaya seed oil showed predominance of monounsaturated fatty acids in its composition. No changes were observed in the acute toxicity test. Had lower food intake in grams, and caloric intake and in the area of adipocytes without minimizing weight gain or adiposity and impacting the liver or pancreas. Reductions in total and non-HDL-c, LDL-c, and VLDL-c were also observed. The treatment had a hypoglycemic and protective effect on insulin resistance. Supplementation also resulted in higher leptin and lower insulin and cytokine resistance.

conclusionsUnder these experimental conditions, papaya seed oil led to higher amounts of monounsaturated fatty acids and had hypocholesterolemic, hypotriglyceridemic, and hypoglycemic effects.

Indexed as

CaricaAdiposityAnimalsCholesterol, LDLDiet, High-FatFatty AcidsFatty Acids, MonounsaturatedHypoglycemic AgentsInsulinInterleukin-6LeptinMiceObesityOlive OilResistinSeedsCholesterol, LDLFatty AcidsFatty Acids, MonounsaturatedHypoglycemic AgentsInsulinInterleukin-6LeptinOlive OilResistinSoybean OilTumor Necrosis Factor-alphaBrazilian fruitdyslipidemiaoil

Identifiers

PMID36235241
PMCPMC9570947
OpenAlexW4303958828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.