Evidence map›Paper›PMID 36235217›Full record

ArticleMolecules (Basel, Switzerland)2022

Antibacterial and Antifungal Silver Nanoparticles with Tunable Size Embedded in Various Cellulose-Based Matrices.

Gabriela Biliuta, Andra-Cristina Bostănaru-Iliescu, Mihai Mareș, Carla Pavlov-Enescu, Valentin Năstasă, Olga Burduniuc, Sergiu Coseri

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Gabriela BiliutaPolyaddition and Photochemistry Laboratory, "Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0001-8600-4149
Andra-Cristina Bostănaru-IliescuLaboratory of Antimicrobial Chemotherapy, Faculty of Veterinary Medicine, "Ion Ionescu de la Brad" University of Life Sciences of Iasi (IULS), 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania.
Mihai MareșLaboratory of Antimicrobial Chemotherapy, Faculty of Veterinary Medicine, "Ion Ionescu de la Brad" University of Life Sciences of Iasi (IULS), 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0000-0002-3103-4954
Carla Pavlov-EnescuLaboratory of Antimicrobial Chemotherapy, Faculty of Veterinary Medicine, "Ion Ionescu de la Brad" University of Life Sciences of Iasi (IULS), 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania.
Valentin NăstasăLaboratory of Antimicrobial Chemotherapy, Faculty of Veterinary Medicine, "Ion Ionescu de la Brad" University of Life Sciences of Iasi (IULS), 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania.
Olga BurduniucDiscipline of Microbiology and Immunology, "Nicolae Testemițanu" State University of Medicine and Pharmacy, Bd. Stefan Cel Mare și Sfant 165, 2001 Chisinau, Moldova.ORCID 0000-0002-6944-0800
Sergiu CoseriPolyaddition and Photochemistry Laboratory, "Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0002-8993-5552
"Ion Ionescu de la Brad" Iasi University of Life Sciences · ROInstitute of Macromolecular Chemistry · UANicolae Testemițanu State University of Medicine and Pharmacy · MD

Funding

Ministry of Research, Innovation and Digitization PN-III-P2-2.1-PED-2019-0169
6 · The paper itself

Abstract

The aim of this study was to synthesize silver nanoparticles (AgNPs) using cellulose derivatives and to evaluate their antimicrobial potential. As effective reducing and stabilizing agents for AgNPs, cellulose derivatives, such as hydroxypropyl cellulose (HPC), methylcellulose (MC), ethylcellulose (EC), and cellulose acetate (CA), were used. Their ability to reduce silver ions as well as the size of the resulting AgNPs were compared. The formation and stability of the reduced AgNPs in the solution were monitored using UV-Vis analysis. The size, morphology, and charge of the AgNPs were evaluated. We found that, when using cellulosic derivatives, AgNPs with sizes ranging from 17 to 89 nm and different stabilities were obtained. The parameters, such as size and ζ potential indicate the stability of AgNPs, with AgNPs-CA and AgNPs-HPC being considered more stable than AgNPs-EC and AgNPs-MC since they show higher ζ potential values. In addition, the AgNPs showed antimicrobial activity against all reference strains and clinical isolates. MIC values between 0.0312 and 0.125 mM had a bactericidal effect on both Gram-positive and Gram-negative bacteria. The fungicidal effect was obtained at a MIC value of 0.125 mM. These results may provide rational support in the design of medical gauze products, including gauze pads, rolls, and sponges.

Indexed as

Anti-Infective AgentsMetal NanoparticlesAnti-Bacterial AgentsAntifungal AgentsCelluloseEscherichia coliExcipientsGram-Negative BacteriaGram-Positive BacteriaMethylcelluloseMicrobial Sensitivity TestsSilverAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsCelluloseExcipientsMethylcelluloseSilverAgNPsantimicrobial activitycellulose acetatecellulose derivativesethylcellulosehydroxypropyl cellulosemethylcellulose

Identifiers

PMID36235217
PMCPMC9573117
OpenAlexW4303958961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.