Evidence map›Paper›PMID 36235183›Full record

ArticleMolecules (Basel, Switzerland)2022

Deep Eutectic Solvents as a Green Tool for the Extraction of Bioactive Phenolic Compounds from Avocado Peels.

Beatriz Rodríguez-Martínez, Pedro Ferreira-Santos, Irene Méndez Alfonso, Sidonia Martínez, Zlatina Genisheva, Beatriz Gullón

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Green Extraction of Phenolic Compounds from Blueberry (Antioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Extraction and Identification of Active Components fromMolecules (Basel, Switzerland) · 2025
    Article
  6. Valorization of Avocado (Antioxidants (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Green Extraction of Antioxidant-Rich Flavonoids fromMolecules (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beatriz Rodríguez-MartínezDepartment of Chemical Engineering, Faculty of Science, University of Vigo (Campus Ourense), As Lagoas, 32004 Ourense, Spain.ORCID 0000-0002-1263-6378
Pedro Ferreira-SantosCentre of Biological Engineering, Universidade do Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-9427-4605
Irene Méndez AlfonsoDepartment of Chemical Engineering, Faculty of Science, University of Vigo (Campus Ourense), As Lagoas, 32004 Ourense, Spain.
Sidonia MartínezDepartment of Chemical Engineering, Faculty of Science, University of Vigo (Campus Ourense), As Lagoas, 32004 Ourense, Spain.ORCID 0000-0002-7897-6754
Zlatina GenishevaCentre of Biological Engineering, Universidade do Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-9367-1385
Beatriz GullónDepartment of Chemical Engineering, Faculty of Science, University of Vigo (Campus Ourense), As Lagoas, 32004 Ourense, Spain.

Funding

Fundação para a Ciência e Tecnologia UIDB/04469/2020LABBELS - Associate Laboratory in Biotechnology, Bioengineering and Microelectromechanical Systems LA/P/0029/2020
6 · The paper itself

Abstract

Avocado peels are the main agro-industrial residue generated during the avocado processing, being a rich source of bioactive compounds like phenolic compounds. The growing demand for more sustainable processes requires the development of new and effective methods for extracting bioactive compounds from industrial waste. Deep eutectic solvents (DESs) are a new sustainable alternative to toxic organic solvents due to their non-toxicity and biocompatibility. In this study, five selected DESs were applied for the extraction of bioactive phenolic compounds from avocado peels. The extraction efficiency was evaluated by measuring the total phenolics and flavonoids content. The best extraction results were obtained with choline chloride-acetic acid and -lactic acid (92.03 ± 2.11 mg GAE/g DAP in TPC and 186.01 ± 3.27 mg RE/g DAP); however, all tested DESs show better extraction efficiency than ethanol. All the obtained NADES extracts have high antioxidant activity (FRAP: 72.5-121.1 mg TE/g; TAC: 90.0-126.1 mg AAE/g). The synthesized DESs and avocado peels DES extracts had activity against all tested bacteria (

Indexed as

Biological ProductsPerseaAnti-Bacterial AgentsAntioxidantsCholineDeep Eutectic SolventsEthanolFlavonoidsIndustrial WasteLactic AcidPhenolsPlant ExtractsSolventsAnti-Bacterial AgentsAntioxidantsBiological ProductsCholineDeep Eutectic SolventsEthanolFlavonoidsIndustrial WasteLactic AcidPhenolsPlant ExtractsSolventsantibacterialantioxidantavocado by-productsgreen extractionnatural deep eutectic solvents

Identifiers

PMID36235183
PMCPMC9572341

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.