Evidence map›Paper›PMID 36235131›Full record

ArticleMolecules (Basel, Switzerland)2022

Two Ways to Achieve the Same Goal-Two Validated Quantitative NMR Strategies for a Low-Abundance Natural Product in Standardized Extracts: The Case of Hepatodamianol in

Aída Parra-Naranjo, Cecilia Delgado-Montemayor, Ricardo Salazar-Aranda, Rocío Castro-Ríos, Alma L Saucedo, Noemí Waksman-Minsky

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aída Parra-NaranjoFacultad de Medicina, Departamento de Química Analítica, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Cecilia Delgado-MontemayorFacultad de Medicina, Departamento de Química Analítica, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.ORCID 0000-0002-4081-5787
Ricardo Salazar-ArandaFacultad de Medicina, Departamento de Química Analítica, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.ORCID 0000-0001-7448-5256
Rocío Castro-RíosFacultad de Medicina, Departamento de Química Analítica, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Alma L SaucedoFacultad de Medicina, Departamento de Química Analítica, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Noemí Waksman-MinskyFacultad de Medicina, Departamento de Química Analítica, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quantification of low-abundance secondary metabolites in plant extracts is an analytical problem that can be addressed by different analytical platforms, the most common being those based on chromatographic methods coupled to a high-sensitivity detection system. However, in recent years nuclear magnetic resonance (NMR) has become an analytical tool of primary choice for this type of problem because of its reliability, inherent simplicity in sample preparation, reduced analysis time, and low solvent consumption. The versatility of strategies based on quantitative NMR (qNMR), such as internal and external standards and electronic references, among others, and the need to develop validated analytical methods make it essential to compare procedures that must rigorously satisfy the analytical well-established acceptance criteria for method validation. In this work, two qNMR methods were developed for the quantification of hepatodamianol, a bioactive component of

Indexed as

Biological ProductsTurneraGoalsMagnetic Resonance SpectroscopyPlant ExtractsReproducibility of ResultsSolventsBiological ProductsPlant ExtractsSolventsdamianamethod validationnatural productsnuclear magnetic resonanceqNMR

Identifiers

PMID36235131
PMCPMC9570796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.