Regioselective Synthesis of 5-Trifluoromethyl 1,2,4-Triazoles via [3 + 2]-Cycloaddition of Nitrile Imines with CF

Bo Lin, Zipeng Zhang, Yunfei Yao, Yi You, Zhiqiang Weng

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Mechanistic Aspects of [3+2] Cycloaddition Reaction of Trifluoroacetonitrile with Diarylnitrilimines in Light of Molecular Electron Density Theory Quantum Chemical Study.Molecules (Basel, Switzerland) · 2024
Article

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5 · Who and what money

Authors and funding

5 authors.

Bo LinKey Laboratory of Molecule Synthesis and Function Discovery, Fujian Provincial Key Laboratory of Electrochemical Energy Storage Materials, College of Chemistry, Fuzhou University, Fuzhou 350108, China.

Zipeng ZhangKey Laboratory of Molecule Synthesis and Function Discovery, Fujian Provincial Key Laboratory of Electrochemical Energy Storage Materials, College of Chemistry, Fuzhou University, Fuzhou 350108, China.

Yunfei YaoKey Laboratory of Molecule Synthesis and Function Discovery, Fujian Provincial Key Laboratory of Electrochemical Energy Storage Materials, College of Chemistry, Fuzhou University, Fuzhou 350108, China.

Yi YouKey Laboratory of Molecule Synthesis and Function Discovery, Fujian Provincial Key Laboratory of Electrochemical Energy Storage Materials, College of Chemistry, Fuzhou University, Fuzhou 350108, China.

Zhiqiang WengKey Laboratory of Molecule Synthesis and Function Discovery, Fujian Provincial Key Laboratory of Electrochemical Energy Storage Materials, College of Chemistry, Fuzhou University, Fuzhou 350108, China.

Funding

National Natural Science Foundation of China 22171124

6 · The paper itself

Abstract

We herein describe a general approach to 5-trifluoromethyl 1,2,4-triazoles via the [3 + 2]-cycloaddition of nitrile imines generated in situ from hydrazonyl chloride with CF

Indexed as

IminesNitrilesChloridesCycloaddition ReactionMolecular StructureOximesTriazolesChloridesIminesNitrilesOximesTriazolescycloadditionnitrile iminestriazoletrifluoroacetonitriletrifluoromethyl

Identifiers

PMID36235104

DOI10.3390/molecules27196568

PMCPMC9572902

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