ReviewMolecules (Basel, Switzerland)2022
Free and Esterified Tocopherols, Tocotrienols and Other Extractable and Non-Extractable Tocochromanol-Related Molecules: Compendium of Knowledge, Future Perspectives and Recommendations for Chromatographic Techniques, Tools, and Approaches Used for Tocochromanol Determination.
Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Comparative analysis of official analytical methods for tocopheryl esters for food additive quality control.Food chemistry: X · 2026Article
- Tocotrienol-Dominated Berberidaceae Species' Seed Tocochromanols: Screening via Ultrasound-Assisted Extraction in Ethanol.Plants (Basel, Switzerland) · 2026Article
- Screening of Tocopherol and Tocotrienol Diversity inMolecules (Basel, Switzerland) · 2026Article
- Taxonomy-Dependent Seed Tocochromanol Composition in the Rutaceae Family: Application of Sustainable Approach for Their Extraction.Plants (Basel, Switzerland) · 2026Article
- Species- and Age-Dependent Prenyllipid Accumulation inPlants (Basel, Switzerland) · 2025Article
- Tocopherol and Tocotrienol Content in the Leaves of the GenusPlants (Basel, Switzerland) · 2025Article
- Tocotrienols in Different Parts of WildMolecules (Basel, Switzerland) · 2025Article
- Tocochromanols in the Leaves of Plants in theMolecules (Basel, Switzerland) · 2025Article
- Tocotrienols in Eleven Species ofMolecules (Basel, Switzerland) · 2025Article
- The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma.Food chemistry. Molecular sciences · 2024Article
- The effect of nitrogen management on seed yield and quality in traditional and canola-quality white mustard.Scientific reports · 2024Article
- Bioactive Compounds and Valorization of Coffee By-Products from the Origin: A Circular Economy Model from Local Practices in Zongolica, Mexico.Plants (Basel, Switzerland) · 2024Article
- Article
- Evaluation of the Content of Minerals, B-Group Vitamins, Tocols, and Carotenoids in Raw and In-House Cooked Wild Edible Plants.Foods (Basel, Switzerland) · 2024Article
- Comprehensive Characterization of Oils and Fats of Six Species from the Colombian Amazon Region with Industrial Potential.Biomolecules · 2023Article
- Effect of Sprouting on Biomolecular and Antioxidant Features of Common Buckwheat (Foods (Basel, Switzerland) · 2023Article
- Tocopherols in Cultivated ApplePlants (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Free and esterified (bound) tocopherols, tocotrienols and other tocochromanol-related compounds, often referred to "tocols", are lipophilic antioxidants of great importance for health. For instance, α-tocopherol is the only tocochromanol with vitamin E activity, while tocotrienols have a positive impact on health and are proposed in the prevention and therapy of so-called modern diseases. Tocopherols, tocotrienols and plastochromanol-8 are the most well-known tocochromanols; in turn, knowledge about tocodienols, tocomonoenols, and other rare tocochromanol-related compounds is limited due to several challenges in analytical chemistry and/or low concentration in plant material. The presence of free, esterified, and non-extractable tocochromanols in plant material as well as their biological function, which may be of great scientific, agricultural and medicinal importance, is also poorly studied. Due to the lack of modern protocols as well as equipment and tools, for instance, techniques suitable for the efficient and simultaneous chromatographical separation of major and minor tocochromanols, the topic requires attention and new solutions, and/or standardization, and proper terminology. This review discusses the advantages and disadvantages of different chromatographic techniques, tools and approaches used for the separation and detection of different tocochromanols in plant material and foodstuffs. Sources of tocochromanols and procedures for obtaining different tocochromanol analytical standards are also described. Finally, future challenges are discussed and perspective green techniques for tocochromanol determination are proposed along with best practice recommendations. The present manuscript aims to present key aspects and protocols related to tocochromanol determination, correct identification, and the interpretation of obtained results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.