ArticleMolecules (Basel, Switzerland)2022
Synthesis of Novel Benzimidazole-Based Thiazole Derivatives as Multipotent Inhibitors of α-Amylase and α-Glucosidase: In Vitro Evaluation along with Molecular Docking Study.
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Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
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Who cites it
22 citing papers in PubMed, 61 citations in OpenAlex.
- A 5-Year Survey on Multiple Targeted Benzimidazole Hybrids.Chemistry & biodiversity · 2026Review
- Magnetic MOF-Based Immunosensing Strategy with Quantum Dot Labeling for Efficient Electro-chemiluminescent Detection of Alpha-fetoprotein.Journal of fluorescence · 2026Article
- Thioflavonols as potent α-glucosidase inhibitors:Future medicinal chemistry · 2025Article
- Introduction of new quinolone-2-thio-acetamide-propane hydrazide-benzimidazole derivatives as new α-glucosidase and α-amylase inhibitors.Scientific reports · 2025Article
- Benzimidazole-Pyrimidine Hybrids: Synthesis and Medicinal Properties.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Computational screening of phytochemicals targeting mutant KRAS in colorectal cancer.Scientific reports · 2025Article
- In-silico analysis of potential phytochemicals targeting mitogen activating protein kinase-14 (MAPK14) gene in colorectal cancer.Scientific reports · 2025Article
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- Synthesis of modified Schiff base appended 1,2,4-triazole hybrids scaffolds: elucidating theZeitschrift fur Naturforschung. C, Journal of biosciences · 2025Article
- Benzimidazole(s): synthons, bioactive lead structures, total synthesis, and the profiling of major bioactive categories.RSC advances · 2025Review
- A Captivating Potential of Schiff Bases Derivatives for Antidiabetic Activity.Current pharmaceutical design · 2025Review
- Discovery of Novel and Selective Schiff Base Inhibitors as a Key for Drug Synthesis, Molecular Docking, and Pharmacological Evaluation.ACS omega · 2024Article
- The Synthesis, In Vitro Bio-Evaluation, and In Silico Molecular Docking Studies of Pyrazoline-Thiazole Hybrid Analogues as Promising Anti-α-Glucosidase and Anti-Urease Agents.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Synthesis of amantadine clubbedRSC advances · 2023Article
- Synthetic transformation of 6-Fluoroimidazo[1,2-a]Pyridine-3-carbaldehyde into 6-Fluoroimidazo[1,2-a]Pyridine-Oxazole Derivatives:Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Synthesis and In Vitro α-Amylase and α-Glucosidase Dual Inhibitory Activities of 1,2,4-Triazole-BearingACS omega · 2023Article
- In Situ Synthesis of a Tumor-Microenvironment-Responsive Chemotherapy Drug.Pharmaceutics · 2023Article
- Blood indices of omega-3 and omega-6 polyunsaturated fatty acids are altered in hyperglycemia.Saudi journal of biological sciences · 2023Article
- Coupling of NIR Spectroscopy and Chemometrics for the Quantification of Dexamethasone in Pharmaceutical Formulations.Pharmaceuticals (Basel, Switzerland) · 2023Article
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Authors and funding
15 authors at 9 institutions in 2 countries.
Rafaqat HussainDepartment of Chemistry, Hazara University, Mansehra 21300, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0003-4810-4776
Shahid IqbalDepartment of Chemistry, School of Natural Sciences (SNS), National University of Science and Technology (NUST), H-12, Islamabad 46000, Pakistan.ORCID 0000-0002-4607-6217
Mazloom ShahDepartment of Chemistry, Abbottabad University of Science and Technology (AUST), Abbottabad 22500, Pakistan.
Wajid RehmanDepartment of Chemistry, Hazara University, Mansehra 21300, Khyber Pakhtunkhwa, Pakistan.
Shoaib KhanDepartment of Chemistry, Hazara University, Mansehra 21300, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0001-5404-0954
Liaqat RasheedDepartment of Chemistry, Hazara University, Mansehra 21300, Khyber Pakhtunkhwa, Pakistan.
Fazal RahimDepartment of Chemistry, Hazara University, Mansehra 21300, Khyber Pakhtunkhwa, Pakistan.
Ayed A DeraDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61413, Saudi Arabia.ORCID 0000-0002-6248-8983
Sana KehiliAdham University College, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Eslam B ElkaeedDepartment of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia.ORCID 0000-0002-2546-8035
Nasser S AwwadChemistry Department, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.ORCID 0000-0002-3477-6996
Majed A BajaberChemistry Department, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.ORCID 0000-0002-2137-5210
Mohammed Issa AlahmdiDepartment of Chemistry, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.
Hamad AlrbyawiPharmaceutics and Pharmaceutical Technology Department, College of Pharmacy, Taibah University, Medina 42353, Saudi Arabia.ORCID 0000-0003-0820-3884
Hashem O AlsaabDepartment of Pharmaceutics and Pharmaceutical Technology, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0001-5448-1004
Hazara University · PKKing Khalid University · SAAbbottabad University of Science and Technology · PKAlfaisal University · SANational University of Sciences and Technology · PKTaibah University · SATaif University · SAUmm al-Qura University · SAUniversity of Tabuk · SA
Funding
King Khalid University RGP.2/167/43Taif University TURSP-2020/67
Abstract
In this study, hybrid analogs of benzimidazole containing a thiazole moiety (
Indexed as
alpha-Amylasesalpha-GlucosidasesAcarboseBenzimidazolesGlycoside Hydrolase InhibitorsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipThiazolesAcarbosealpha-Amylasesalpha-GlucosidasesBenzimidazolesGlycoside Hydrolase InhibitorsThiazolesbenzimidazole bearing thiazole analogsmolecular dockingsynthesisα-amylaseα-glucosidase
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.