Evidence map›Paper›PMID 36234918›Full record

ArticleMolecules (Basel, Switzerland)2022

A Green Chemical Approach for Iodination of Pyrimidine Derivatives by Mechanical Grinding under Solvent-Free Conditions.

Thananjeyan Balasubramaniyam, Byeong-Seon Kim, Badvel Pallavi, Ho-Seong Jin, Sung Kuk Kim, Joon-Hwa Lee

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thananjeyan BalasubramaniyamDepartment of Chemistry and RINS, Gyeongsang National University, Jinju 52828, Korea.
Byeong-Seon KimDepartment of Chemistry Education and RINS, Gyeongsang National University, Jinju 52828, Korea.
Badvel PallaviDepartment of Chemistry Education and RINS, Gyeongsang National University, Jinju 52828, Korea.
Ho-Seong JinDepartment of Chemistry and RINS, Gyeongsang National University, Jinju 52828, Korea.
Sung Kuk KimDepartment of Chemistry and RINS, Gyeongsang National University, Jinju 52828, Korea.ORCID 0000-0001-6995-1144
Joon-Hwa LeeDepartment of Chemistry and RINS, Gyeongsang National University, Jinju 52828, Korea.ORCID 0000-0003-3137-4585

Funding

National Research Foundation of Korea 2020R1A2C1006909National Research Foundation of Korea 2022R1A4A1021817Samsung Science and Technology Foundation SSTF-BA1701-10
6 · The paper itself

Abstract

The iodination of pyrimidines is usually carried out by using toxic reagents under acidic conditions, such as with sulfuric acid and nitric acid. To avoid toxic reagents, we developed a simple and eco-friendly approach for the iodination of pyrimidine derivatives under solvent-free conditions using solid iodine and AgNO

Indexed as

HalogenationIodineIndicators and ReagentsNitric AcidPyrimidinesSolventsIndicators and ReagentsIodineNitric AcidPyrimidinesSolventsgreen synthesismechanochemistrynitrate saltspyrimidine derivatives

Identifiers

PMID36234918
PMCPMC9571335

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.