Evidence map›Paper›PMID 36234910›Full record

ReviewMolecules (Basel, Switzerland)2022

In Silico Evaluation of Natural Flavonoids as a Potential Inhibitor of Coronavirus Disease.

Piyush Kashyap, Mamta Thakur, Nidhi Singh, Deep Shikha, Shiv Kumar, Poonam Baniwal, Yogender Singh Yadav, Minaxi Sharma, Kandi Sridhar, Baskaran Stephen Inbaraj

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Bioinformatics Study of Flavonoids From GenusAdvances and applications in bioinformatics and chemistry : AABC · 2024
    Article
  10. Article
  11. Preliminary Evaluation ofACS omega · 2023
    Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 4 countries.

Piyush KashyapDepartment of Food Technology and Nutrition, School of Agriculture, Lovely Professional University, Phagwara 144401, India.
Mamta ThakurDepartment of Food Technology, School of Sciences, ITM University, Gwalior 474001, India.ORCID 0000-0002-6052-6819
Nidhi SinghCentre of Bioinformatics, University of Allahabad, Prayraj 211002, India.
Deep ShikhaDepartment of Food Technology, Bhai Gurdas Institute of Engineering and Technology, Sangrur 148001, India.
Shiv KumarMMICT & BM (HM), Maharishi Markandeshwar Deemed to be University, Mullana, Ambala 133207, India.ORCID 0000-0003-0655-9561
Poonam BaniwalDepartment of Quality Control, Food Corporation of India, New Delhi 110001, India.
Yogender Singh YadavDepartment of Dairy Engineering, College of Dairy Science and Technology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar 125004, India.ORCID 0000-0001-6638-9926
Minaxi SharmaLaboratoire de Chimieverte et Produits Biobasés, Département AgroBioscience et Chimie, Haute Ecole Provinciale du Hainaut-Condorcet, 11, 7800 ATH Rue de la Sucrerie, Belgium.ORCID 0000-0001-6493-5217
Kandi SridharUMR1253, Science et Technologie du Lait et de l'œuf, INRAE, L'InstitutAgro, Rennes-Angers, 65 Rue de Saint Brieuc, F-35042 Rennes, France.ORCID 0000-0002-6174-0024
Baskaran Stephen InbarajDepartment of Food Science, Fu Jen Catholic University, New Taipei City 242 05, Taiwan.ORCID 0000-0003-4301-7614
Fu Jen Catholic University · TWHaute École Provinciale de Hainaut Condorcet · BEInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRITM University · INLala Lajpat Rai University of Veterinary and Animal Sciences · INLovely Professional University · INMaharishi Markandeshwar University, Mullana · INUniversity of Allahabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent coronavirus disease (COVID-19) outbreak in Wuhan, China, has led to millions of infections and the death of approximately one million people. No targeted therapeutics are currently available, and only a few efficient treatment options are accessible. Many researchers are investigating active compounds from natural plant sources that may inhibit COVID-19 proliferation. Flavonoids are generally present in our diet, as well as traditional medicines and are effective against various diseases. Thus, here, we reviewed the potential of flavonoids against crucial proteins involved in the coronavirus infectious cycle. The fundamentals of coronaviruses, the structures of SARS-CoV-2, and the mechanism of its entry into the host's body have also been discussed. In silico studies have been successfully employed to study the interaction of flavonoids against COVID-19 M

Indexed as

COVID-19 Drug TreatmentDiosminHesperidinAntiviral AgentsFlavonoidsHumansLopinavirMolecular Docking SimulationNelfinavirRitonavirRutinSARS-CoV-2Spike Glycoprotein, CoronavirusAntiviral AgentsDiosminFlavonoidsHesperidinLopinavirNelfinavirRitonavirRutinSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2ACE2COVID-19flavonoidsin silico studiesMpro

Identifiers

PMID36234910
PMCPMC9572657
OpenAlexW4297546906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.