Evidence map›Paper›PMID 36234773›Full record

ArticleMolecules (Basel, Switzerland)2022

Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.

Jin-Fang Luo, Hua Zhou, Chon-Kit Lio

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  13. Triterpenoid and Coumarin Isolated fromMolecules (Basel, Switzerland) · 2023
    Article
  14. Molecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Jin-Fang LuoBasic Medical College, Guizhou University of Traditional Chinese Medicine, Guian District, Guiyang 550025, China.
Hua ZhouGuangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Dampness Syndrome of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medcine and Immune Disease Research, Guangzhou 510006, China.ORCID 0000-0002-7025-3690
Chon-Kit LioFaculty of Chinese Medicine, Macau University of Science and Technology and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao 999078, China.
Guangzhou University of Chinese Medicine · CNGuizhou University · CNMacau University of Science and Technology · MO

Funding

Special research project on science and technology of traditional Chinese medicine and ethnic medicine in Guizhou Province QZYY-2021-012Young scientific and technological talents growth project of Guizhou Provincial Department of Education [2021]194
6 · The paper itself

Abstract

Akebia saponin D (ASD) is derived from the

Indexed as

Interleukin-6NF-E2-Related Factor 2Anti-Inflammatory AgentsDinoprostoneDNAHumansInflammationInflammation MediatorsLipopolysaccharidesMethyltransferasesNF-kappa BNitric OxideNitric Oxide Synthase Type IIRNA, MessengerRNA, Small InterferingSaponinsakebia saponin DAnti-Inflammatory AgentsDinoprostoneDNAInflammation MediatorsInterleukin-6LipopolysaccharidesMethyltransferasesNF-E2-Related Factor 2NF-kappa BNitric OxideNitric Oxide Synthase Type IIRNA, MessengerRNA, Small InterferingSaponinsSTAT3 protein, humanSTAT3 Transcription FactorTumor Necrosis Factor-alphaAkbia saponin DDipsacus asper Wall. ex HenryDNMT3bNrf2p-STAT3

Identifiers

PMID36234773
PMCPMC9614599
OpenAlexW4297006175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.