Evidence map›Paper›PMID 36234772›Full record

ArticleMolecules (Basel, Switzerland)2022

Fate of Sulfonamides and Tetracyclines in Meat during Pan Cooking: Focus on the Thermodegradation of Sulfamethoxazole.

Christelle Planche, Sylvie Chevolleau, Maria-Hélèna Noguer-Meireles, Isabelle Jouanin, Sophie Mompelat, Jérémy Ratel, Eric Verdon, Erwan Engel, Laurent Debrauwer

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Christelle PlancheINRAE, UR370 QuaPA, MASS Group, F-63122 Saint-Genès-Champanelle, France.ORCID 0000-0002-7751-4603
Sylvie ChevolleauToxalim, Université de Toulouse, INRAE UMR 1331, INP-ENVT, INP-EI-Purpan, UPS, F-31027 Toulouse, France.
Maria-Hélèna Noguer-MeirelesToxalim, Université de Toulouse, INRAE UMR 1331, INP-ENVT, INP-EI-Purpan, UPS, F-31027 Toulouse, France.
Isabelle JouaninToxalim, Université de Toulouse, INRAE UMR 1331, INP-ENVT, INP-EI-Purpan, UPS, F-31027 Toulouse, France.
Sophie MompelatANSES, French Agency for Food, Environmental and Occupational Health & Safety, Laboratory of Fougères, Javené, F-35306 Fougères, France.
Jérémy RatelINRAE, UR370 QuaPA, MASS Group, F-63122 Saint-Genès-Champanelle, France.
Eric VerdonANSES, French Agency for Food, Environmental and Occupational Health & Safety, Laboratory of Fougères, Javené, F-35306 Fougères, France.
Erwan EngelINRAE, UR370 QuaPA, MASS Group, F-63122 Saint-Genès-Champanelle, France.
Laurent DebrauwerToxalim, Université de Toulouse, INRAE UMR 1331, INP-ENVT, INP-EI-Purpan, UPS, F-31027 Toulouse, France.
Université Toulouse III - Paul Sabatier · FRCentre Hospitalier de Fougères · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FR

Funding

Agence Nationale de la Recherche Project SOMEAT, Contract No. ANR-12-ALID-0004
6 · The paper itself

Abstract

Although antimicrobials are generally found in trace amounts in meat, the human health risk they bear cannot be ignored. With the ultimate aim of making a better assessment of consumer exposure, this study explored the effects of pan cooking on sulfonamides and tetracyclines in meat. Screening of these antimicrobials in cooked meat was first performed by the European Union Reference Laboratory on the basis of HPLC-MS/MS analyses. A proof of concept approach using radiolabeling was then carried out on the most cooking-sensitive antimicrobial-sulfamethoxazole-to assess if a thermal degradation could explain the observed cooking losses. Degradation products were detected thanks to separation by HPLC and monitoring by online radioactivity detection. HPLC-Orbitrap HRMS analyses completed by 1D and 2D NMR experiments allowed the structural characterization of these degradation compounds. This study revealed that cooking could induce significant antimicrobial losses of up to 45% for sulfamethoxazole. Six potential degradation products of

Indexed as

Heterocyclic CompoundsTetracyclinesAnti-Bacterial AgentsCookingHumansMeatSulfamethoxazoleSulfanilamideSulfonamidesTandem Mass SpectrometryAnti-Bacterial AgentsHeterocyclic CompoundsSulfamethoxazoleSulfanilamideSulfonamidesTetracyclinesbeef meatcookingdegradation productsradiolabelingsulfonamidestetracyclines

Identifiers

PMID36234772
PMCPMC9571958
OpenAlexW4296993566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.