Evidence map›Paper›PMID 36234717›Full record

ReviewMolecules (Basel, Switzerland)2022

Phosphatidylcholine Cation-Tyrosine π Complexes: Motifs for Membrane Binding by a Bacterial Phospholipase C.

Mary F Roberts, Anne Gershenson, Nathalie Reuter

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Spider venom phospholipase D toxin structure: Interfacial binding site, mechanism, activation, and head group preference.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Alchemical Free Energy Calculations on Membrane-Associated Proteins.Journal of chemical theory and computation · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Mary F RobertsDepartment of Chemistry, Boston College, Chestnut Hill, MA 02467, USA.ORCID 0000-0003-3547-951X
Anne GershensonDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0003-3124-9610
Nathalie ReuterComputational Biology Unit, Department of Informatics and Chemistry, University of Bergen, 5020 Bergen, Norway.ORCID 0000-0002-3649-7675
Boston College · USUniversity of Bergen · NOUniversity of Massachusetts Amherst · US

Funding

ACTIVATION OF PI-SPECIFIC PHOSPHOLIPASE C ENZYMESR01GM060418 · NIGMS · BOSTON COLLEGE · PI ROBERTS, MARY FEDARKO · 2000 to 2013
$3.1M
NIGMS NIH HHS R01 GM060418NIH HHS GM60418 (M.F.R. and A.G.)Norwegian Research Council FRIMEDBIO #214167 and FRIMEDBIO #251247. (N.R,)
6 · The paper itself

Abstract

Phosphatidylinositol-specific phospholipase C (PI-PLC) enzymes are a virulence factor in many Gram-positive organisms. The specific activity of the

Indexed as

Type C PhospholipasesTyrosineCationsCholineLecithinsPhosphatidylinositolsPhosphoinositide Phospholipase CVirulence FactorsCationsCholineLecithinsPhosphatidylinositolsPhosphoinositide Phospholipase CType C PhospholipasesTyrosineVirulence Factorsallosteric effectorcation-π interactionmolecular dynamic simulationsNMR relaxometryphosphatidylcholinephosphatidylinositolPI-specific phospholipase C

Identifiers

PMID36234717
PMCPMC9572076
OpenAlexW4296848674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.