Evidence map›Paper›PMID 36234683›Full record

ArticleMolecules (Basel, Switzerland)2022

Mycobacterium Time-Series Genome Analysis Identifies AAC2' as a Potential Drug Target with Naloxone Showing Potential Bait Drug Synergism.

Vidya Niranjan, Akshay Uttarkar, Keerthana Murali, Swarna Niranjan, Jayalatha Gopal, Jitendra Kumar

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. In Vitro and In Vivo Effects of Resveratrol on Rat Hepatic CYP1A2.Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Selection of Multi-Drug Targets against Drug-ResistantInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vidya NiranjanDepartment of Biotechnology, R. V. College of Engineering, Mysuru Road, Kengeri, Bangalore 560059, India.ORCID 0000-0001-9187-7753
Akshay UttarkarDepartment of Biotechnology, R. V. College of Engineering, Mysuru Road, Kengeri, Bangalore 560059, India.ORCID 0000-0001-9326-1426
Keerthana MuraliDepartment of Biotechnology, R. V. College of Engineering, Mysuru Road, Kengeri, Bangalore 560059, India.
Swarna NiranjanDepartment of Artificial Intelligence and Machine Learning, R. V. College of Engineering, Mysuru Road, Kengeri, Bangalore 560059, India.
Jayalatha GopalDepartment of Mathematics, R. V. College of Engineering, Mysuru Road, Kengeri, Bangalore 560059, India.
Jitendra KumarBangalore Bioinnovation Centre, Helix Biotech Park, Electronic City Phase 1, Bangalore 560100, India.
R.V. College of EngineeringBiotech Park · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization has put drug resistance in tuberculosis on its list of significant threats, with a critical emphasis on resolving the genetic differences in Mycobacterium tuberculosis. This provides an opportunity for a better understanding of the evolutionary progression leading to anti-microbial resistance. Anti-microbial resistance has a great impact on the economic stability of the global healthcare sector. We performed a timeline genomic analysis from 2003 to 2021 of 578

Indexed as

Mycobacterium tuberculosisTuberculosisAminesAminoglycosidesAntitubercular AgentsDrug SynergismGentamicinsHumansMolecular Docking SimulationMolecular Dynamics SimulationNaloxoneAminesAminoglycosidesAntitubercular AgentsGentamicinsNaloxoneAAC2′drug repurposingdrug synergismgenome analysisMetadynamicsMycobacterium tuberculosistime-series

Identifiers

PMID36234683
PMCPMC9571707
OpenAlexW4296740991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.