Evidence map›Paper›PMID 36234557›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Dynamic Fluid Flow Exacerbates the (Pro-)Inflammatory Effects of Aerosolised Engineered Nanomaterials In Vitro.

Kirsty Meldrum, Joana A Moura, Shareen H Doak, Martin J D Clift

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kirsty MeldrumIn Vitro Toxicology Group, Swansea University Medical School, Swansea University, Wales SA2 8PP, UK.ORCID 0000-0002-2658-6850
Joana A MouraIn Vitro Toxicology Group, Swansea University Medical School, Swansea University, Wales SA2 8PP, UK.
Shareen H DoakIn Vitro Toxicology Group, Swansea University Medical School, Swansea University, Wales SA2 8PP, UK.ORCID 0000-0002-6753-1987
Martin J D CliftIn Vitro Toxicology Group, Swansea University Medical School, Swansea University, Wales SA2 8PP, UK.ORCID 0000-0001-6133-3368
Swansea University · GB

Funding

Horizon 2020 Research and Innovation Programme 760813 (PATROLS)
6 · The paper itself

Abstract

The majority of in vitro studies focusing upon particle-lung cell interactions use static models at an air-liquid interface (ALI). Advancing the physiological characteristics of such systems allows for closer resemblance of the human lung, in turn promoting 3R strategies. PATROLS (EU Horizon 2020 No. 760813) aimed to use a well-characterised in vitro model of the human alveolar epithelial barrier to determine how fluid-flow dynamics would impact the outputs of the model following particle exposure. Using the QuasiVivo

Indexed as

aerosol exposureco-culturefluid flowin vitrolungmicro-fluidicsnanoparticlesquasi-ALI exposure

Identifiers

PMID36234557
PMCPMC9565225
OpenAlexW4302018442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.