ArticleNanomaterials (Basel, Switzerland)2022
Curcumin Sustained Release with a Hybrid Chitosan-Silk Fibroin Nanofiber Containing Silver Nanoparticles as a Novel Highly Efficient Antibacterial Wound Dressing.
Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 82 citations in OpenAlex.
- A mechanically robust and moisture-retentive hydrocolloid dressing for chronic wound management.Scientific reports · 2026Article
- Kaempferol-based nanocarriers as a potential therapeutic strategy against drug-resistant lung cancer.Cancer cell international · 2026Review
- Mucoadhesive nanofibers for ocular drug delivery: mechanisms, design strategies, and applications.Drug delivery and translational research · 2026Review
- Silver Nanoparticle-Silk Protein Nanocomposites: A Synergistic Biomimetic Approach for Advanced Antimicrobial Applications.Biomimetics (Basel, Switzerland) · 2025Review
- Chitosan Nanoparticle-Based Drug Delivery Systems: Advances, Challenges, and Future Perspectives.Polymers · 2025Review
- Review
- l-Carnosine loaded on carboxymethyl cellulose hydrogels for promoting wound healing.RSC advances · 2024Article
- Intelligent electrospinning nanofibrous membranes for monitoring and promotion of the wound healing.Materials today. Bio · 2024Review
- Electrospinning Silk-Fibroin-Based Fibrous Membranes with AgNPs for Antimicrobial Application.Polymers · 2024Article
- Chitosan-Based Scaffolds Incorporated with Silver Nanoparticles for the Treatment of Infected Wounds.Pharmaceutics · 2024Review
- Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry.Animals : an open access journal from MDPI · 2024Review
- Improved cell growth on additively manufactured Ti64 substrates with varying porosity and nanofibrous coating.Heliyon · 2024Article
- Silk Fibroin Materials: Biomedical Applications and Perspectives.Bioengineering (Basel, Switzerland) · 2024Review
- Modified in-vitro AATCC-100 procedure to measure viable bacteria from wound dressings.PloS one · 2024Article
- Self-Sanitizing Polycaprolactone Electrospun Nanofiber Membrane with Ag Nanoparticles.Journal of functional biomaterials · 2023Article
- Review
- Silver Nanoparticles Loaded on Chitosan-g-PVA Hydrogel for the Wound-Healing Applications.Molecules (Basel, Switzerland) · 2023Article
- Biopolymer Composites 2022.International journal of molecular sciences · 2023Article
- Electrospun core-sheath PCL nanofibers loaded with nHA and simvastatin and their potential bone regeneration applications.Frontiers in bioengineering and biotechnology · 2023Article
- Microcurrent Cloth-Assisted Transdermal Penetration and Follicular Ducts Escape of Curcumin-Loaded Micelles for Enhanced Wound Healing.International journal of nanomedicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Drug loading in electrospun nanofibers has gained a lot of attention as a novel method for direct drug release in an injury site to accelerate wound healing. The present study deals with the fabrication of silk fibroin (SF)-chitosan (CS)-silver (Ag)-curcumin (CUR) nanofibers using the electrospinning method, which facilitates the pH-responsive release of CUR, accelerates wound healing, and improves mechanical properties. Response surface methodology (RSM) was used to investigate the effect of the solution parameters on the nanofiber diameter and morphology. The nanofibers were characterized via Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), zeta potential, and Dynamic Light Scattering (DLS). CS concentration plays a crucial role in the physical and mechanical properties of the nanofibers. Drug loading and entrapment efficiencies improved from 13 to 44% and 43 to 82%, respectively, after the incorporation of Ag nanoparticles. The application of CS hydrogel enabled a pH-responsive release of CUR under acid conditions. The Minimum Inhibitory Concentration (MIC) assay on
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.