Evidence map›Paper›PMID 36234263›Full record

ArticleMaterials (Basel, Switzerland)2022

Essential Oils as Antimicrobial Active Substances in Wound Dressings.

Daniela Gheorghita, Elena Grosu, Alina Robu, Lia Mara Ditu, Iuliana Mihaela Deleanu, Gratiela Gradisteanu Pircalabioru, Anca-Daniela Raiciu, Ana-Iulia Bita, Aurora Antoniac, Vasile Iulian Antoniac

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

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  18. Wound Dressing Modifications for Accelerated Healing of Infected Wounds.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Daniela GheorghitaFaculty of Material Science and Engineering, University Politehnica of Bucharest, 313 Splaiul Independentei Street, 060042 Bucharest, Romania.ORCID 0000-0003-3660-8926
Elena GrosuFaculty of Material Science and Engineering, University Politehnica of Bucharest, 313 Splaiul Independentei Street, 060042 Bucharest, Romania.
Alina RobuFaculty of Material Science and Engineering, University Politehnica of Bucharest, 313 Splaiul Independentei Street, 060042 Bucharest, Romania.
Lia Mara DituFaculty of Biology, University of Bucharest, 1-3 Intr. Portocalelor Street, 060101 Bucharest, Romania.ORCID 0000-0002-6593-255X
Iuliana Mihaela DeleanuFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Polizu Street, 011061 Bucharest, Romania.ORCID 0000-0003-0597-0789
Gratiela Gradisteanu PircalabioruResearch Institute of the University of Bucharest, 90 Sos. Panduri, 050663 Bucharest, Romania.
Anca-Daniela RaiciuFaculty of Pharmacy, Titu Maiorescu University, 22 Dambovnicului Street, 040441 Bucharest, Romania.
Ana-Iulia BitaFaculty of Material Science and Engineering, University Politehnica of Bucharest, 313 Splaiul Independentei Street, 060042 Bucharest, Romania.
Aurora AntoniacFaculty of Material Science and Engineering, University Politehnica of Bucharest, 313 Splaiul Independentei Street, 060042 Bucharest, Romania.
Vasile Iulian AntoniacFaculty of Material Science and Engineering, University Politehnica of Bucharest, 313 Splaiul Independentei Street, 060042 Bucharest, Romania.ORCID 0000-0003-0112-3494
Universitatea Națională de Știință și Tehnologie Politehnica București · ROUniversity of Bucharest · ROAcademia Oamenilor de Știință din România · ROTitu Maiorescu University · RO

Funding

Competitiveness Operational Program 2014-2020, Action 1.1.3 "UPB4H", financed by contract: 250/11.05.2020Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P2-2.1.-PED-2019-5236
6 · The paper itself

Abstract

Wound dressings for skin lesions, such as bedsores or pressure ulcers, are widely used for many patients, both during hospitalization and in subsequent treatment at home. To improve the treatment and shorten the healing time and, therefore, the cost, numerous types of wound dressings have been developed by manufacturers. Considering certain inconveniences related to the intolerance of some patients to antibiotics and the antimicrobial, antioxidant, and curative properties of certain essential oils, we conducted research by incorporating these oils, based on polyvinyl alcohol/ polyvinyl pyrrolidone (PVA/PVP) biopolymers, into dressings. The objective of this study was to study the potential of a polymeric matrix for wound healing, with polyvinyl alcohol as the main material and polyvinyl pyrrolidone and hydroxypropyl methylcellulose (HPMC) as secondary materials, together with additives (plasticizers poly(ethylene glycol) (PEG) and glycerol), stabilizers (Zn stearate), antioxidants (vitamin A and vitamin E), and four types of essential oils (fennel, peppermint, pine, and thyme essential oils). For all the studied samples, the combining compatibility, antimicrobial, and cytotoxicity properties were investigated. The obtained results demonstrated a uniform morphology for almost all the samples and adequate barrier properties for contact with suppurating wounds. The results show that the obtained samples containing essential oils have a good inhibitory effect on, or antimicrobial properties against,

Indexed as

antimicrobial propertiesbiopolymerscytotoxicityessential oilshydrogelsmicroencapsulationMTT assaywound healing

Identifiers

PMID36234263
PMCPMC9570933
OpenAlexW4303832762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.