Evidence map›Paper›PMID 36234190›Full record

ArticleMaterials (Basel, Switzerland)2022

Microstructure and Mechanical Properties of Hot-Extruded Mg-Zn-Ga-(Y) Biodegradable Alloys.

Viacheslav Bazhenov, Anna Li, Stanislav Tavolzhanskii, Andrey Bazlov, Natalia Tabachkova, Andrey Koltygin, Alexander Komissarov, Kwang Seon Shin

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Viacheslav BazhenovCasting Department, National University of Science and Technology "MISiS", Leninskiy pr. 4, 119049 Moscow, Russia.ORCID 0000-0003-3214-1935
Anna LiLaboratory of Hybrid Nanostructured Materials, National University of Science and Technology "MISiS", Leninskiy pr. 4, 119049 Moscow, Russia.
Stanislav TavolzhanskiiCasting Department, National University of Science and Technology "MISiS", Leninskiy pr. 4, 119049 Moscow, Russia.
Andrey BazlovLaboratory of Advanced Green Materials, National University of Science and Technology "MISiS", Leninskiy pr. 4, 119049 Moscow, Russia.ORCID 0000-0002-0409-1056
Natalia TabachkovaDepartment of Materials Science of Semiconductors and Dielectrics, National University of Science and Technology "MISiS", Leninskiy pr. 4, 119049 Moscow, Russia.ORCID 0000-0002-0169-5014
Andrey KoltyginCasting Department, National University of Science and Technology "MISiS", Leninskiy pr. 4, 119049 Moscow, Russia.ORCID 0000-0002-8376-0480
Alexander KomissarovLaboratory of Hybrid Nanostructured Materials, National University of Science and Technology "MISiS", Leninskiy pr. 4, 119049 Moscow, Russia.ORCID 0000-0001-5125-9870
Kwang Seon ShinLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, Delegatskaya 20/1, 127473 Moscow, Russia.ORCID 0000-0002-2902-0027

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2021-696Ministry of Science and Higher Education of the Russian Federation 075-15-2022-1133
6 · The paper itself

Abstract

Magnesium alloys are attractive candidates for use as temporary fixation devices in osteosynthesis because they have a density and Young's modulus similar to those of cortical bone. One of the main requirements for biodegradable implants is its substitution by tissues during the healing process. In this article, the Mg-Zn-Ga-(Y) alloys were investigated that potentially can increase the bone growth rate by release of Ga ions during the degradation process. Previously, the effectiveness of Ga ions on bone tissue regeneration has been proved by clinical tests. This work is the first systematic study on the microstructure and mechanical properties of Mg-Zn-Y alloys containing Ga as an additional major alloying element prepared by the hot-extrusion process. The microstructure and phase composition of the Mg-Zn-Ga-(Y) alloys in as-cast, heat-treated, and extruded conditions were analyzed. In addition, it was shown that the use of hot extrusion produces Mg-Zn-Ga-(Y) alloys with favorable mechanical properties. The tensile yield strength, ultimate tensile strength, and elongation at fracture of the MgZn4Ga4 alloy extruded at 150 °C were 256 MPa, 343 MPa, and 14.2%, respectively. Overall, MgZn4Ga4 alloy is a perspective for applications in implants for osteosynthesis with improved bone regeneration ability.

Indexed as

biomaterialsgalliumhot extrusionmagnesiummechanical propertiesmicrostructure

Identifiers

PMID36234190
PMCPMC9572374

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.