Evidence map›Paper›PMID 36234047›Full record

ArticleMaterials (Basel, Switzerland)2022

Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond.

Long Liu, Shun He, Zhiming Guo, Jian Li, Mingchun Zhao, Yiping Wu

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Long LiuDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, China.
Shun HeDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, China.
Zhiming GuoDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, China.
Jian LiDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, China.
Mingchun ZhaoSchool of Materials Science and Engineering, Central South University, Changsha 410083, China.ORCID 0000-0003-3145-7188
Yiping WuDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, China.
Changsha University · CNCentral South University · CN

Funding

Changsha University Talent Introduction Scientific Research Fund SF2140Excellent youth project of Hunan Provincial Department of Education 19B055Scientific Research Fund of Hunan Provincial Education Department 21C0750 and 19C0168The Key Research and Development Projects of Changsha kq2203005
6 · The paper itself

Abstract

The Mg-6Zn-0.5Zr (ZK60) alloy has attracted extensive attention as one of the hopeful biomedical material candidates for bone implant applications on account of its unique degradability, favorable biocompatibility as well as mechanical compatibility. Nevertheless, the rapid degradation rate in the biological environment is the major hurdle for its clinical application in the field of bone implants. In this study, nanodiamond (ND) was incorporated into ZK60 alloy via selective laser melting technology to enhance its degradation resistance. The results showed that compared with selective laser-melted ZK60 (SLMed ZK60), the selective laser-melted ZK60 with 6 wt.% ND (SLMed ZK60-6ND) possessed the better degradation resistance with the lower degradation rate of 0.5 ± 0.1 mm/year. The enhancement of the degradation resistance was attributed to the fact that ND could promote the deposition of apatite and build up a dense and insoluble protective layer through the dissociation of the carboxyl groups on the ND surface, which could effectively hinder the further degradation of the Mg matrix. Meanwhile, the compressive strength and hardness were improved mainly due to grain refinement strengthening and ND dispersion strengthening. In addition, the SLMed ZK60-6ND possessed good cytocompatibility. These results suggested that the SLMed ZK60-6ND, with enhanced degradation resistance, improved mechanical properties, and good cytocompatibility, was an excellent biomedical material candidate for bone implant applications.

Indexed as

apatite layerdegradation resistanceMg alloysnanodiamondselective laser melting

Identifiers

PMID36234047
PMCPMC9571488
OpenAlexW4297541924

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.