Evidence map›Paper›PMID 36233833›Full record

ReviewJournal of clinical medicine2022

Long-Term Management of Pulmonary Embolism: A Review of Consequences, Treatment, and Rehabilitation.

Anette Arbjerg Højen, Peter Brønnum Nielsen, Thure Filskov Overvad, Ida Ehlers Albertsen, Frederikus A Klok, Nanna Rolving, Mette Søgaard, Anne Gulbech Ording

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Psychological Impact of Pulmonary Embolism: A Narrative Review.Journal of community hospital internal medicine perspectives · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Association Between Heart Rate at Diagnosis and Long-Term Recurrence Risk of Pulmonary Embolism in a Historical Cohort Study of Elder Women.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Anette Arbjerg HøjenUnit for Thrombosis and Drug Research, Aalborg University Hospital, 9000 Aalborg, Denmark.
Peter Brønnum NielsenUnit for Thrombosis and Drug Research, Aalborg University Hospital, 9000 Aalborg, Denmark.
Thure Filskov OvervadUnit for Thrombosis and Drug Research, Aalborg University Hospital, 9000 Aalborg, Denmark.ORCID 0000-0001-8096-0236
Ida Ehlers AlbertsenUnit for Thrombosis and Drug Research, Aalborg University Hospital, 9000 Aalborg, Denmark.
Frederikus A KlokDepartment of Medicine-Thrombosis and Hemostasis, Leiden University Medical Center, 2333 Leiden, The Netherlands.ORCID 0000-0001-9961-0754
Nanna RolvingDepartment of Physical and Occupational Therapy, Aarhus University Hospital, 8200 Aarhus, Denmark.ORCID 0000-0001-9195-7278
Mette SøgaardUnit for Thrombosis and Drug Research, Aalborg University Hospital, 9000 Aalborg, Denmark.
Anne Gulbech OrdingUnit for Thrombosis and Drug Research, Aalborg University Hospital, 9000 Aalborg, Denmark.
Aalborg University Hospital · DKAarhus University · DKLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concept of pulmonary embolism is evolving. Recent and emerging evidence on the treatment of specific patient populations, its secondary prevention, long-term complications, and the unmet need for rehabilitation has the potential to change clinical practice for the benefit of the patients. This review discusses the recent evidence from clinical trials, observational studies, and guidelines focusing on anticoagulation treatment, rehabilitation, emotional stress, quality of life, and the associated outcomes for patients with pulmonary embolism. Guidelines suggest that the type and duration of treatment with anticoagulation should be based on prevalent risk factors. Recent studies demonstrate that an anticoagulant treatment that is longer than two years may be effective and safe for some patients. The evidence for extended treatment in cancer patients is limited. Careful consideration is particularly necessary for pulmonary embolisms in pregnancy, cancer, and at the end of life. The rehabilitation and prevention of unnecessary deconditioning, emotional distress, and a reduced quality of life is an important, but currently they are unmet priorities for many patients with a pulmonary embolism. Future research could demonstrate optimal anticoagulant therapy durations, follow-ups, and rehabilitation, and effective patient-centered decision making at the end of life. A patient preferences and shared decision making should be incorporated in their routine care when weighing the benefits and risks with primary treatment and secondary prevention.

Indexed as

anticoagulationbleedingcancer-associated thrombosislong-term managementpatient preferencespulmonary embolismrecurrencerehabilitationreview

Identifiers

PMID36233833
PMCPMC9571065
OpenAlexW4304136266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.