Evidence map›Paper›PMID 36233728›Full record

ArticleJournal of clinical medicine2022

Cardiovascular Function in Different Phases of the Menstrual Cycle in Healthy Women of Reproductive Age.

Malgorzata Kwissa, Tomasz Krauze, Agnieszka Mitkowska-Redman, Beata Banaszewska, Robert Z Spaczynski, Andrzej Wykretowicz, Przemyslaw Guzik

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Endocrine modulation of cortical and retinal baseline perfusion across the menstrual cycle.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Malgorzata KwissaDepartment of Cardiology-Intensive Care Therapy and Internal Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0001-9796-5746
Tomasz KrauzeDepartment of Cardiology-Intensive Care Therapy and Internal Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Agnieszka Mitkowska-RedmanDivision of Infertility and Reproductive Endocrinology, Department of Gynaecology, Obstetrics, and Gynaecological Oncology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Beata BanaszewskaDivision of Infertility and Reproductive Endocrinology, Department of Gynaecology, Obstetrics, and Gynaecological Oncology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Robert Z SpaczynskiDivision of Infertility and Reproductive Endocrinology, Department of Gynaecology, Obstetrics, and Gynaecological Oncology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-4306-6590
Andrzej WykretowiczDepartment of Cardiology-Intensive Care Therapy and Internal Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Przemyslaw GuzikDepartment of Cardiology-Intensive Care Therapy and Internal Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0001-9052-5027
Poznan University of Medical Sciences · PL

Funding

Polish National Science Center N407 297640
6 · The paper itself

Abstract

Background: Sex hormones influence the cardiovascular (CV) function in women. However, it is uncertain whether their physiological variation related to the regular menstrual cycle affects the CV system. We studied changes in the hemodynamic profile and body’s water content and their relation to sex hormone concentration in healthy women during the menstrual cycle. Material and methods: Forty-five adult women were examined during the early follicular, late follicular, and mid-luteal phases of the same menstrual cycle. The hemodynamic profile was estimated non-invasively by cardiac impedance while water content was estimated by total body impedance. Results were compared with repeated measures ANOVA with post-test, if applicable. Results: There were no significant changes in most hemodynamic and water content parameters between the menstrual cycle phases in healthy women. Left ventricular ejection time differed significantly among phases of the menstrual cycle, with shorter values in the mid-luteal phase (308.4 vs. 313.52 ms, p < 0.05) compared to the late follicular phase. However, the clinical relevance of such small differences is negligible. Conclusions: Changes in sex hormones during the physiological menstrual cycle appear to have no considerable effect on healthy women’s hemodynamic function and water accumulation.

Indexed as

blood pressurebody water contenthemodynamic functionmenstrual cyclesex hormones

Identifiers

PMID36233728
PMCPMC9572726
OpenAlexW4303709983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.