Evidence map›Paper›PMID 36233701›Full record

ReviewJournal of clinical medicine2022

The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis.

Vasileios Siokas, Robert Fleischmann, Katharina Feil, Ioannis Liampas, Markus C Kowarik, Yang Bai, Maria-Ioanna Stefanou, Sven Poli, Ulf Ziemann, Efthimios Dardiotis and 1 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Post-Operative Delirium in Elderly Patients: A Narrative Review.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vasileios SiokasDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.
Robert FleischmannDepartment of Neurology, University Medicine Greifswald, 17475 Greifswald, Germany.ORCID 0000-0001-8159-2658
Katharina FeilDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-4566-712X
Ioannis LiampasDepartment of Neurology, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41100 Larissa, Greece.ORCID 0000-0002-2958-5220
Markus C KowarikDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.
Yang BaiDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.
Maria-Ioanna StefanouDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.
Sven PoliDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-0286-8781
Ulf ZiemannDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-8372-3615
Efthimios DardiotisDepartment of Neurology, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41100 Larissa, Greece.ORCID 0000-0003-2957-641X
Annerose MengelDepartment of Neurology & Stroke, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-2399-3020

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular risk factors may predispose to post-stroke delirium (PSD). A systematic review and meta-analysis were performed by searching PubMed, Web of Science, and Scopus. The primary outcome was the prevalence of vascular risk factors in PSD vs. non-PSD patients. Odds ratios (ORs) with 95% confidence intervals (CIs) and mean differences (MDs) with 95% CIs were calculated for categorical and continuous variables, respectively. Fixed effects or random effects models were used in case of low- or high-statistical heterogeneity, respectively. We found an increased prevalence of atrial fibrillation (OR = 1.74, p = 0.0004), prior stroke (OR = 1.48, p < 0.00001), coronary artery disease (OR = 1.48, p < 0.00001), heart failure (OR = 2.01, p < 0.0001), and peripheral vascular disease (OR = 2.03, p < 0.00001) in patients with vs. without PSD. PSD patients were older (MD = 5.27 y, p < 0.00001) compared with their non-PSD counterparts. Advanced age, atrial fibrillation, prior stroke, coronary artery disease, heart failure, and peripheral vascular disease appeared to be significantly associated with PSD.

Indexed as

deliriumPSDstrokevascular risk factors

Identifiers

PMID36233701
PMCPMC9571874

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.