Evidence map›Paper›PMID 36233627›Full record

ArticleJournal of clinical medicine2022

Prevalence and Risk Factor Analysis of Post-Intensive Care Syndrome in Patients with COVID-19 Requiring Mechanical Ventilation: A Multicenter Prospective Observational Study.

Junji Hatakeyama, Shigeaki Inoue, Keibun Liu, Kazuma Yamakawa, Takeshi Nishida, Shinichiro Ohshimo, Satoru Hashimoto, Naoki Kanda, Shuhei Maruyama, Yoshitaka Ogata and 26 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 2 countries.

Junji HatakeyamaDepartment of Emergency and Critical Care Medicine, National Hospital Organization Tokyo Medical Center, Tokyo 152-8902, Japan.ORCID 0000-0003-2290-6965
Shigeaki InoueDepartment of Disaster and Emergency Medicine, School of Medicine, Kobe University, Kobe 650-0017, Japan.ORCID 0000-0003-3907-8537
Keibun LiuCritical Care Research Group, The Prince Charles Hospital, Brisbane, QLD 4032, Australia.ORCID 0000-0002-6867-1420
Kazuma YamakawaDepartment of Emergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.ORCID 0000-0003-2999-4021
Takeshi NishidaDivision of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka 558-8558, Japan.
Shinichiro OhshimoDepartment of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.ORCID 0000-0003-1119-3322
Satoru HashimotoDepartment of Intensive Care Medicine, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Naoki KandaDivision of General Internal Medicine, Jichi Medical University Hospital, Tochigi 329-0498, Japan.
Shuhei MaruyamaDepartment of Emergency and Critical Care Medicine, Kansai Medical University Medical Center, Osaka 570-8507, Japan.
Yoshitaka OgataDepartment of Critical Care Medicine, Yao Tokushukai General Hospital, Osaka 581-0011, Japan.
Daisuke KawakamiDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe 650-0047, Japan.
Hiroaki ShimizuAcute Care Medical Center, Hyogo Prefectural Kakogawa Medical Center, Kakogawa 675-8555, Japan.
Katsura HayakawaDepartment of Emergency and Critical Care Medicine, Saitama Red Cross Hospital, Saitama 330-8553, Japan.
Aiko TanakaDepartment of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.ORCID 0000-0002-8990-1336
Taku OshimaDepartment of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Tatsuya FuchigamiIntensive Care Unit, University of the Ryukyus Hospital, Nishihara 903-0215, Japan.
Hironori YawataDepartment of Emergency and Critical Care Medicine, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto 605-0981, Japan.
Kyoji OeDepartment of Intensive Care Medicine, Asahi General Hospital, Chiba 289-2511, Japan.
Akira KawauchiJapanese Red Cross Maebashi Hospital, Advanced Medical Emergency Department and Critical Care Center, Maebashi 371-0811, Japan.
Hidehiro YamagataAdvanced Critical Care and Emergency Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Masahiro HaradaDepartment of Emergency and Critical Care, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.ORCID 0000-0002-0162-5390
Yuichi SatoCritical Care and Emergency Center, Metropolitan Tama General Medical Center, Tokyo 183-8524, Japan.
Tomoyuki NakamuraDepartment of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine, Nagoya 470-1192, Japan.ORCID 0000-0002-8348-4092
Kei SugikiDepartment of Intensive Care Medicine, Yokohama City Minato Red Cross Hospital, Yokohama 231-8682, Japan.
Takahiro HakozakiDepartment of Anesthesiology, Fukushima Medical University, Fukushima 960-1295, Japan.
Satoru BeppuDepartment of Emergency and Critical Care Medicine, National Hospital Organization Kyoto Medical Center, Kyoto 612-8555, Japan.ORCID 0000-0002-1434-5697
Masaki AnrakuDepartment of Thoracic Surgery, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo 173-0015, Japan.
Noboru KatoDepartment of Emergency and Critical Care Medicine, Yodogawa Christian Hospital, Osaka 533-0024, Japan.
Tomomi IwashitaDepartment of Emergency and Critical Care Center, Nagano Red Cross Hospital, Nagano 380-8582, Japan.
Hiroshi KamijoDepartment of Emergency and Critical Care Medicine, Shinshu University Hospital, Nagano 390-8621, Japan.
Yuichiro KitagawaEmergency and Disaster Medicine, Gifu University School of Medicine Graduate School of Medicine, Gifu 501-1194, Japan.
Michio NagashimaDepartment of Intensive Care Medicine, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.ORCID 0000-0001-7416-5367
Hirona NishimakiDepartment of Anesthesiology, Tohoku University Hospital, Sendai 980-8574, Japan.
Kentaro TokudaIntensive Care Unit, Kyushu University Hospital, Fukuoka 812-8582, Japan.
Osamu NishidaDepartment of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine, Nagoya 470-1192, Japan.ORCID 0000-0003-0140-283X
Kensuke NakamuraDepartment of Emergency and Critical Care Medicine, Hitachi General Hospital, Hitachi 317-0077, Japan.ORCID 0000-0001-8481-0294
Fujita Health University · JPAsahi General Hospital · JPChiba University · JPFukushima Medical University · JPGifu University · JPHiroshima University · JPHitachi General Hospital · JPJichi Medical University · JPKansai Medical University · JPKobe City Medical Center General Hospital · JPKobe University · JPKumamoto Medical Center · JPKyoto first Red Cross hospital · JPKyoto Medical Center · JPKyoto Prefectural University of Medicine · JPKyushu University Hospital · JPMaebashi Red Cross Hospital · JPNagano Red Cross Hospital · JPOsaka Prefectural Medical Center · JPOsaka University of Pharmaceutical Sciences · JP

Funding

Nestlé Health Science Company of Nestlé Japan none
6 · The paper itself

Abstract

introductionPost-intensive care syndrome (PICS) is an emerging problem in critically ill patients and the prevalence and risk factors are unclear in patients with severe coronavirus disease 2019 (COVID-19). This multicenter prospective observational study aimed to investigate the prevalence and risk factors of PICS in ventilated patients with COVID-19 after ICU discharge.

methodsQuestionnaires were administered twice in surviving patients with COVID-19 who had required mechanical ventilation, concerning Barthel Index, Short-Memory Questionnaire, and Hospital Anxiety and Depression Scale scores. The risk factors for PICS were examined using a multivariate logistic regression analysis.

resultsThe first and second PICS surveys were obtained at 5.5 and 13.5 months (mean) after ICU discharge, with 251 and 209 patients completing the questionnaires and with a prevalence of PICS of 58.6% and 60.8%, respectively, along with the highest percentages of cognitive impairment. Delirium (with an odds ratio of (OR) 2.34, 95% CI 1.1-4.9, and

conclusionApproximately 60% of the ventilated patients with COVID-19 experienced persistent PICS, especially delirium, and required longer mechanical ventilation.

Indexed as

COVID-19critically ill patientsdeliriumpost-intensive care syndrome

Identifiers

PMID36233627
PMCPMC9571505
OpenAlexW4297477512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.