ReviewJournal of clinical medicine2022
Face Transplant: Indications, Outcomes, and Ethical Issues-Where Do We Stand?
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oral health and rehabilitation in face transplant recipients - a systematic review.Clinical oral investigations · 2025Pooled it
- Facial vascularized composite allotransplantation: Mapping global research trends and scientific impact.JPRAS open · 2026Review
- Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review.Clinical anatomy (New York, N.Y.) · 2026Review
- Reassessing Ethical Considerations in Pediatric Facial Transplantation: Where Are We Now?Plastic and reconstructive surgery. Global open · 2026Article
- Cutaneous Malignancy Risk in Facial and Hand Vascularized Composite Allotransplantation Recipients: A Review of Immunosuppressive Regimens and Their Oncologic Impact.Life (Basel, Switzerland) · 2026Review
- Rewiring faces: advances and outcomes in facial nerve reconstruction after facial vascularized composite allotransplantation.Frontiers in surgery · 2026Review
- Clustering and predicting VCA patient populations - a machine learning approach into vascularized composite allotransplantation.Frontiers in immunology · 2026Article
- Management of Avulsive Soft Tissue Ballistic Facial Injuries.Seminars in plastic surgery · 2025Review
- Vascularised Composite Allotransplantation - A guide to optimal dissemination of scientific outputs.Journal of hand and microsurgery · 2025Article
- Effectiveness and Role of Using Hyaluronic Acid Injections for Gluteal Augmentation: A Comprehensive Systematic Review of Techniques and Outcomes.Aesthetic plastic surgery · 2024Article
- Preauricular Aging: A Three-Point Grading System to Guide Treatment in Facial Rejuvenation.Aesthetic plastic surgery · 2024Article
- Porcine Acellular Dermal Matrix Increases Fat Survival Rate After Fat Grafting in Nude Mice.Aesthetic plastic surgery · 2024Article
- Effect of Preoperative Subcutaneous Platelet-Rich Plasma and Fibrin Glue Application on Skin Flap Survival.Aesthetic plastic surgery · 2024Article
- Breast Reconstruction: Developing a Volumetric Outcome Algorithm.Aesthetic plastic surgery · 2024Article
- Staged Stem Cell-Enriched Tissue (SET) Injections for Soft Tissue Augmentation in Hostile Recipient Areas: A Preliminary Report.Aesthetic plastic surgery · 2024Article
- A Novel Technique Combining Human Acellular Dermal Matrix (HADM) and Enriched Platelet Therapy (EPT) for the Treatment of Vaginal Laxity: A Single-Arm, Observational Study.Aesthetic plastic surgery · 2024Article
- Adipose Tissue-Derived Stem Cells in Plastic and Reconstructive Surgery: A Bibliometric Study.Aesthetic plastic surgery · 2024Article
- Cell-Assisted Lipotransfer: A Systematic Review of its Efficacy.Aesthetic plastic surgery · 2024Article
- Clinical Application of Platelet-Rich Fibrin in Plastic and Reconstructive Surgery: A Systematic Review.Aesthetic plastic surgery · 2024Article
- A Novel Autologous Scaffold for Diced-Cartilage Grafts in Dorsal Augmentation Rhinoplasty.Aesthetic plastic surgery · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The addition of face allotransplantation (FT) to the head and neck reconstructive surgery arsenal has started a true revolution. This study is aimed at providing an extensive analysis of the current practice of composite tissue allotransplantation. Moreover, a thorough description of pre-procedural, intra-operative, and post-procedural settings, indications, contraindications, outcomes, ethical considerations, and future perspectives is provided. Methods: The authors’ experience was supplemented with a literature review performed by using the PubMed, MEDLINE, and Embase databases on 21 February 2022. The search terms used were “face transplantation indications”, “face transplantation complications”, and “face transplantation ethical issues”. Results: The most recent achievements and long-term clinical sequelae of FT are classified and summarized. A large number of records (4435) were identified. Seventy-five articles were assessed for eligibility. Publications without new data and reports with a patient follow-up < 5 years were excluded. Nineteen articles met the criteria for inclusion. Conclusions: The most recent achievements in the field of FT may be combined with cutting-edge regenerative medicine procedures and innovative immunological processing. It is paramount to build strong international networks between the world FT experts in order to achieve higher-level outcomes and reduce the complication rate. Nevertheless, the utmost caution is required in patient selection, clinical assessment, strict follow-up, and rejection management.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.