Evidence map›Paper›PMID 36233593›Full record

ArticleJournal of clinical medicine2022

Meeting the Challenges of Myocarditis: New Opportunities for Prevention, Detection, and Intervention-A Report from the 2021 National Heart, Lung, and Blood Institute Workshop.

Daniela Čiháková, Yang Shi, Bishow Adhikari, W Patricia Bandettini, Madeleine W Cunningham, Narasimhan Danthi, Matthias G Friedrich, Peter Liu, Lisa Schwartz Longacre, Douglas L Mann and 5 more

Open access · goldAbstract readConference Proceedings
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Injury-induced myosin-specific tissue-resident memory T cells drive immune checkpoint inhibitor myocarditis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. HomozygousGenes · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 2 countries.

Daniela ČihákováDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-8713-2860
Yang ShiDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Bishow AdhikariDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
W Patricia BandettiniDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Madeleine W CunninghamDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Narasimhan DanthiDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Matthias G FriedrichDepartment of Diagnostic Radiology, McGill University Health Centre, Montreal, QC H4A 3J1, Canada.
Peter LiuDepartment of Medicine and Cellular Molecular Medicine, University of Ottawa, Ottawa, ON K1Y 4W7, Canada.
Lisa Schwartz LongacreDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Douglas L MannCenter for Cardiovascular Research, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-2516-0145
Filip K SwirskiCardiovascular Research Institute and the Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
W H Wilson TangDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-8335-735X
Guofei ZhouDivision of Lung Diseases, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Leslie T CooperDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, FL 32224, USA.ORCID 0000-0003-1002-3313
Workshop Speakers
National Institutes of Health · USCleveland Clinic · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USMayo Clinic in Florida · USMcGill University Health Centre · CAUniversity of Oklahoma Health Sciences Center · USUniversity of Ottawa · CAWashington University in St. Louis · US

Funding

Macrophages in homeostasis and cardiovascular diseaseR35HL135752 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SWIRSKI, FILIP K · 2017 to 2023
$5.4M
NHLBI NIH HHS R35 HL135752
6 · The paper itself

Abstract

The National Heart, Lung, and Blood Institute (NHLBI) convened a workshop of international experts to discuss new research opportunities for the prevention, detection, and intervention of myocarditis in May 2021. These experts reviewed the current state of science and identified key gaps and opportunities in basic, diagnostic, translational, and therapeutic frontiers to guide future research in myocarditis. In addition to addressing community-acquired myocarditis, the workshop also focused on emerging causes of myocarditis including immune checkpoint inhibitors and SARS-CoV-2 related myocardial injuries and considered the use of systems biology and artificial intelligence methodologies to define workflows to identify novel mechanisms of disease and new therapeutic targets. A new priority is the investigation of the relationship between social determinants of health (SDoH), including race and economic status, and inflammatory response and outcomes in myocarditis. The result is a proposal for the reclassification of myocarditis that integrates the latest knowledge of immunological pathogenesis to refine estimates of prognosis and target pathway-specific treatments.

Indexed as

cardiac magnetic resonancecytokinesdilated cardiomyopathyheart biopsyheart failurelymphocytesmacrophagesmyocarditisNHLBI workshop in myocarditisviral myocarditis

Identifiers

PMID36233593
PMCPMC9571285
OpenAlexW4297538840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.