Evidence map›Paper›PMID 36233261›Full record

ReviewInternational journal of molecular sciences2022

Emerging Roles of the α-Catenin Family Member α-Catulin in Development, Homeostasis and Cancer Progression.

Mateusz Gielata, Kamila Karpińska, Tomasz Pieczonka, Agnieszka Kobielak

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mateusz GielataLaboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.
Kamila KarpińskaLaboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.
Tomasz PieczonkaLaboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0002-6249-9754
Agnieszka KobielakLaboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0002-9293-0787
University of Warsaw · PL

Funding

Polish National Science Center 2017/25/B/NZ5/01597Polish National Science Center 2020/37/B/NZ5/03950
6 · The paper itself

Abstract

α-catulin, together with vinculin and the α-catenins, belongs to the vinculin family of proteins, best known for their actin-filament binding properties and crucial roles in cell-cell and cell-substrate adhesion. In the past few years, an array of binding partners for α-catulin have surfaced, which has shed new light on the possible functions of this protein. Despite all this information, the molecular basis of how α-catulin acts in cells and controls a wide variety of signals during morphogenesis, tissue homeostasis, and cancer progression remains elusive. This review aims to highlight recent discoveries on how α-catulin is involved in a broad range of diverse biological processes with an emphasis on cancer progression.

Indexed as

CateninsNeoplasmsActinsalpha CateninFamilyHomeostasisHumansVinculinActinsalpha CateninCateninsVinculincateninCTNNAL1EMTepithelial-mesenchymal transitioninvasionvascular mimicryα-catulin

Identifiers

PMID36233261
PMCPMC9569426
OpenAlexW4303710111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.