Evidence map›Paper›PMID 36233226›Full record

ArticleInternational journal of molecular sciences2022

Design, Synthesis and Biological Evaluation of Neocryptolepine Derivatives as Potential Anti-Gastric Cancer Agents.

Yunhao Ma, Yanan Tian, Zhongkun Zhou, Shude Chen, Kangjia Du, Hao Zhang, Xinrong Jiang, Juan Lu, Yuqing Niu, Lixue Tu and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Yunhao MaSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0003-4680-3661
Yanan TianSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Zhongkun ZhouSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Shude ChenThe Second Clinical Medical College, Lanzhou University, Lanzhou 730000, China.
Kangjia DuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0002-5420-7440
Hao ZhangSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Xinrong JiangSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Juan LuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Yuqing NiuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Lixue TuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Jie WangSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Huanxiang LiuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0002-9284-3667
Hongmei ZhuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Peng ChenSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0003-4402-4568
Yingqian LiuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Lanzhou University · CNLanzhou University Second Hospital · CN

Funding

Innovation and Entrepreneurship Training Program of Lanzhou University, China cxcy202207National College Students' Innovation and Entrepreneurship Training Program 202210730011the College Students' Innovation and Entrepreneurship Training Program of Lanzhou University, China 20220260010the Key Program for International S&T Cooperation Projects of China Gansu Province 18YF1WA115the Key Research and Development Program of Gansu Province 21YF5FA112the Technological Innovation Guidance Program of Gansu Province 21CX6QA127
6 · The paper itself

Abstract

Natural products play an important role in drug development and lead compound synthesis. Neocryptolepine is a polycyclic quinoline compound isolated from

Indexed as

Antineoplastic AgentsBiological ProductsQuinolinesStomach NeoplasmsAlkaloidsApoptosisCell Line, TumorCell ProliferationHumansMolecular Docking SimulationPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktAlkaloidsAntineoplastic AgentsBiological ProductsneocryptolepinePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktQuinolinesAGS cellAKTHGC27 cellneocryptolepine derivativesPI3K/AKT signaling pathway

Identifiers

PMID36233226
PMCPMC9569688
OpenAlexW4303709925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.