Evidence map›Paper›PMID 36233202›Full record

ArticleInternational journal of molecular sciences2022

The Antitumor Effect of Timosaponin A3 through c-Myc Inhibition in Colorectal Cancer Cells and Combined Treatment Effect with 5-FU or Doxorubicin.

Hyun Min Ko, Wona Jee, Do-Il Park, Kwan-Il Kim, Ji Hoon Jung, Hyeung-Jin Jang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. International journal of molecular sciences · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hyun Min KoCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0001-6184-7748
Wona JeeCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0003-1110-3171
Do-Il ParkCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Kwan-Il KimDivision of Allergy, Immune and Respiratory System, Department of Internal Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-8071-3881
Ji Hoon JungCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-5644-5960
Hyeung-Jin JangCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-4996-9053
Kyung Hee University · KR

Funding

Korea Health Industry Development Institute HF20C0030National Research Foundation of Korea 2020R1C1C1009348
6 · The paper itself

Abstract

Timosaponin A3 (TA3), extracted from the rhizome of

Indexed as

Colonic NeoplasmsColorectal NeoplasmsApoptosisCaspase 3Cell Line, TumorCell ProliferationDoxorubicinFluorouracilHCT116 CellsHumansPoly(ADP-ribose) Polymerase InhibitorsRepressor ProteinsSaponinsSteroidsCaspase 3CNOT2 protein, humanDoxorubicinFluorouracilPoly(ADP-ribose) Polymerase InhibitorsRepressor ProteinsSaponinsSteroidstimosaponin AIIIc-MycCNOT2HCT116MID1IP1Timosaponin A3

Identifiers

PMID36233202
PMCPMC9569550
OpenAlexW4303710092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.