Evidence map›Paper›PMID 36233002›Full record

ArticleInternational journal of molecular sciences2022

Responses of Ileal and Fecal Microbiota to Withdrawal of Pancreatic Enzyme Replacement Therapy in a Porcine Model of Exocrine Pancreatic Insufficiency.

Julia Hankel, Anne Mößeler, Clara Berenike Hartung, Silke Rath, Lisa Schulten, Christian Visscher, Josef Kamphues, Marius Vital

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Julia HankelInstitute for Animal Nutrition, University of Veterinary Medicine Hannover, 30173 Hanover, Germany.ORCID 0000-0002-4347-3161
Anne MößelerInstitute for Animal Nutrition, University of Veterinary Medicine Hannover, 30173 Hanover, Germany.
Clara Berenike HartungInstitute for Animal Nutrition, University of Veterinary Medicine Hannover, 30173 Hanover, Germany.
Silke RathMicrobial Interactions and Processes Group, Helmholtz Centre for Infection Research, 30628 Braunschweig, Germany.ORCID 0000-0002-2132-8174
Lisa SchultenInstitute for Animal Nutrition, University of Veterinary Medicine Hannover, 30173 Hanover, Germany.
Christian VisscherInstitute for Animal Nutrition, University of Veterinary Medicine Hannover, 30173 Hanover, Germany.ORCID 0000-0003-1497-5709
Josef KamphuesInstitute for Animal Nutrition, University of Veterinary Medicine Hannover, 30173 Hanover, Germany.
Marius VitalInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, 30625 Hannover, Germany.
University of Veterinary Medicine Hannover, Foundation · DEHelmholtz Centre for Infection Research · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known regarding the interplay between microbiota and pancreas functions in humans as investigations are usually limited to distal sites, namely the analyses of fecal samples. The aim of this study was to investigate both ileal and fecal microbiota in response to pancreatic enzyme replacement therapy (PERT) in a porcine model of exocrine pancreatic insufficiency (EPI). PERT was stopped for ten days in ileo-cecal fistulated minipigs with experimentally induced EPI (

Indexed as

Exocrine Pancreatic InsufficiencyMicrobiotaAnimalsBacteriaEnzyme Replacement TherapyFecesHumansIleumPancreasSwineSwine, Miniatureexocrine pancreas insufficiencygut microbiotamaldigestionminipigssmall intestine

Identifiers

PMID36233002
PMCPMC9570030
OpenAlexW4303699695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.